CAJ | 학술논문

NLRP3炎症小体是固有免疫系统识别受体家族主要成员，最新研究发现NLRP3炎症小体在银屑病皮损处高表达。炎症小体激活后可活化caspase－1(含半胱氨酸的天冬氨酸水解酶)及分泌大量炎症细胞因子，促进银屑病炎症的病理反应。 NLRP3炎症小体可能参与银屑病的炎症反应过程。
NLRP3염증소체시고유면역계통식별수체가족주요성원，최신연구발현NLRP3염증소체재은설병피손처고표체。염증소체격활후가활화caspase－1(함반광안산적천동안산수해매)급분비대량염증세포인자，촉진은설병염증적병리반응。 NLRP3염증소체가능삼여은설병적염증반응과정。
NLRP3 inflammasomes is one of the recognition receptor family members of the innate immune systems. The expression of NLRP3 inflammasomes is high in the lesions of psoriasis. Caspase-1 ( Cysteine-containing aspartate hydrolase) is activated and the secretion of inflammatory cytokines is promoted after the inflammasome activated. NLRP3 inflammasmes may be involved in the inflammation process of psoriasis.