中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2015年
8期
5-7
,共3页
放置左炔诺孕酮宫内缓释系统%子宫切除术%经前期症状%卵巢功能%心理健康
放置左炔諾孕酮宮內緩釋繫統%子宮切除術%經前期癥狀%卵巢功能%心理健康
방치좌결낙잉동궁내완석계통%자궁절제술%경전기증상%란소공능%심리건강
Placing levonorgestrel-releasing intrauterine system%Hysterectomy%Premenstrual syndrome%Ovarian function%Mental health syndrome
目的 探讨放置左炔诺孕酮宫内缓释系统(LNG-IUS)和子宫切除术两种长效治疗方法对月经过多患者的经前期症状(头痛、乳房压痛、易激惹/神经质、疲劳/感情淡漠、肿胀)、卵巢功能、心理健康(抑郁、焦虑)等方面的影响.方法 采用整群抽样的方法,将2012年9月至2013年9月在郑州大学人民医院门诊就诊及妇科住院并符合条件的月经过多患者165例经知情同意后纳入该研究队列,根据患者意愿将患者分为两组.Ⅰ组(83例):经期末在超声引导下宫内放置LNG-IUS;Ⅱ组(82例):择期在全身麻醉下行子宫切除术.分析两种长效治疗方法对月经过多患者的经前期症状(头痛、乳房压痛、易激惹/神经质、疲劳/感情淡漠、肿胀)、卵巢功能、心理健康(抑郁、焦虑)等方面的影响.结果 治疗后6个月两组患者经前期症状均明显减少(P＜0.05),两组患者血清FSH和雌二醇水平、焦虑(STAI量表)、抑郁(BDI量表)评分结果变化量比较差异未见统计学意义(P＞0.05);治疗后12个月两组患者经前期症状无明显变化(P＞0.05),Ⅱ组患者血清FSH平均水平高于Ⅰ组患者,差异有统计学意义(P＜0.05).两组患者焦虑、抑郁评分结果变化量未见明显差异(P＞0.05).结论 放置LNG-IUS和子宫切除术相比,后者可能会影响卵巢功能,表现为血清FSH水平升高,这两种治疗方法对患者经前期症状改变、心理变化比较差异未见统计学意义.
目的 探討放置左炔諾孕酮宮內緩釋繫統(LNG-IUS)和子宮切除術兩種長效治療方法對月經過多患者的經前期癥狀(頭痛、乳房壓痛、易激惹/神經質、疲勞/感情淡漠、腫脹)、卵巢功能、心理健康(抑鬱、焦慮)等方麵的影響.方法 採用整群抽樣的方法,將2012年9月至2013年9月在鄭州大學人民醫院門診就診及婦科住院併符閤條件的月經過多患者165例經知情同意後納入該研究隊列,根據患者意願將患者分為兩組.Ⅰ組(83例):經期末在超聲引導下宮內放置LNG-IUS;Ⅱ組(82例):擇期在全身痳醉下行子宮切除術.分析兩種長效治療方法對月經過多患者的經前期癥狀(頭痛、乳房壓痛、易激惹/神經質、疲勞/感情淡漠、腫脹)、卵巢功能、心理健康(抑鬱、焦慮)等方麵的影響.結果 治療後6箇月兩組患者經前期癥狀均明顯減少(P＜0.05),兩組患者血清FSH和雌二醇水平、焦慮(STAI量錶)、抑鬱(BDI量錶)評分結果變化量比較差異未見統計學意義(P＞0.05);治療後12箇月兩組患者經前期癥狀無明顯變化(P＞0.05),Ⅱ組患者血清FSH平均水平高于Ⅰ組患者,差異有統計學意義(P＜0.05).兩組患者焦慮、抑鬱評分結果變化量未見明顯差異(P＞0.05).結論 放置LNG-IUS和子宮切除術相比,後者可能會影響卵巢功能,錶現為血清FSH水平升高,這兩種治療方法對患者經前期癥狀改變、心理變化比較差異未見統計學意義.
목적 탐토방치좌결낙잉동궁내완석계통(LNG-IUS)화자궁절제술량충장효치료방법대월경과다환자적경전기증상(두통、유방압통、역격야/신경질、피로/감정담막、종창)、란소공능、심리건강(억욱、초필)등방면적영향.방법 채용정군추양적방법,장2012년9월지2013년9월재정주대학인민의원문진취진급부과주원병부합조건적월경과다환자165례경지정동의후납입해연구대렬,근거환자의원장환자분위량조.Ⅰ조(83례):경기말재초성인도하궁내방치LNG-IUS;Ⅱ조(82례):택기재전신마취하행자궁절제술.분석량충장효치료방법대월경과다환자적경전기증상(두통、유방압통、역격야/신경질、피로/감정담막、종창)、란소공능、심리건강(억욱、초필)등방면적영향.결과 치료후6개월량조환자경전기증상균명현감소(P＜0.05),량조환자혈청FSH화자이순수평、초필(STAI량표)、억욱(BDI량표)평분결과변화량비교차이미견통계학의의(P＞0.05);치료후12개월량조환자경전기증상무명현변화(P＞0.05),Ⅱ조환자혈청FSH평균수평고우Ⅰ조환자,차이유통계학의의(P＜0.05).량조환자초필、억욱평분결과변화량미견명현차이(P＞0.05).결론 방치LNG-IUS화자궁절제술상비,후자가능회영향란소공능,표현위혈청FSH수평승고,저량충치료방법대환자경전기증상개변、심리변화비교차이미견통계학의의.
Objective To analyze the effects of the placement of levonorgestrel releasing intrauterine system(LNG-IUS) and hysterectomy on menorrhagia premenstrual symptoms (such as headache,breast tenderness,irritability/nervousness,fatigue/feelings of apathy,swelling),ovarian function,mental health (depression,anxiety),etc.Methods A cluster sampling program was conducted to divide a total of 165 gynecological qualified menorrhagia patients who were in the inpatient and outpatient of the People' s Hospital of Zhengzhou University during September 2012 and September 2013 into two groups according to the willing of patients.Group Ⅰ (83 cases):The ultrasound-guided intrauterine levonorgestrel releasing intrauterine system was placed at the end of the period ; Group Ⅱ (82 cases):hysterectomy were conducted in general anesthesia.The influence of two long-term treatment on menorrhagia premenstrual symptoms (headache,breast tenderness,irritability/nervousness,fatigue/feeling of apathy,swelling),ovarian function,mental health (depression,anxiety) were analyzed.Results Premenstrual syndrome were significantly reduced (P ＜ 0.05) at six months post-treatment.There was no significant difference in serum FSH or estradiol levels,anxiety (STAI scale),depression (BDI Scale) score results variation between two groups of patients (P ＞ 0.05).No significant change at 12 months post treatment (P ＞ 0.05) in terms of premenstrual symptoms.Serum FSH levels of the Group Ⅱ was higher than the average levels of Group Ⅰ,and the difference was statistically significant (P ＜ 0.05).The anxiety,depression score results variation of the two groups of patients has no obvious difference (P ＞ 0.05).Conclusions Compared with placing LNG-IUS,hysterectomy may affect ovarian function,manifested as elevated serum FSH levels,the two kinds of treatments make no significant difference for changing the symptoms and psychological states of patients with premenstrual.
