CAJ | 학술논문

目的探讨帕金森病患者音乐情绪认知的特点、与执行功能的关系及其影响因素.方法采用24首表达高兴、悲伤、恐惧、愤怒情绪的音乐节选对2014年1月至6月在北京医院神经内科就诊的24例帕金森病患者和24名健康对照进行测试.两组均采用一个简化了的连线测验和画钟测验进行执行功能检查.对所有患者应用Hoehn-Yahr(H-Y)分期、统一帕金森病评定量表第三部分(UPDRS Ⅲ)、汉密尔顿焦虑量表(HAMA)、汉密尔顿抑郁量表(HAMD)及左旋多巴等效剂量(LDE)等对临床特点进行评定.结果帕金森病患者的连线时间[(51.58 ±33.14)s]较对照组[(34.46±19.64)s]明显延长(t=2.178,P=0.036),中位连线错误次数[0(QL =0,QU=2.5)]较对照组[0(QL=0,QU=0)]明显增加(Z=-2.372,P=0.018),画钟测验分数(2.63±0.65)较对照组(2.96±0.20)明显降低(t=-2.407,P=0.023).帕金森病组在识别高兴、悲伤、恐惧和愤怒音乐时与对照组差异没有统计学意义(均P＞0.05).帕金森病组识别高兴、悲伤音乐情绪得分以及总分均与连线时间存在明显相关性(r=-0.560、-0.572、-0.530,P=0.004、0.003、0.008),而与年龄、病程、受教育时间、简易精神状态量表评分、UPDRSⅢ评分、H-Y分期、HAMA评分、HAMD评分、LDE、画钟测验得分和音乐背景均无明显相关性(均P ＞0.05).结论本组帕金森病患者的音乐情绪认知未受损;音乐情绪认知与执行功能之间的关系尚不确定.
목적 탐토파금삼병환자음악정서인지적특점、여집행공능적관계급기영향인소.방법 채용24수표체고흥、비상、공구、분노정서적음악절선대2014년1월지6월재북경의원신경내과취진적24례파금삼병환자화24명건강대조진행측시.량조균채용일개간화료적련선측험화화종측험진행집행공능검사.대소유환자응용Hoehn-Yahr(H-Y)분기、통일파금삼병평정량표제삼부분(UPDRS Ⅲ)、한밀이돈초필량표(HAMA)、한밀이돈억욱량표(HAMD)급좌선다파등효제량(LDE)등대림상특점진행평정.결과 파금삼병환자적련선시간[(51.58 ±33.14)s]교대조조[(34.46±19.64)s]명현연장(t=2.178,P=0.036),중위련선착오차수[0(QL =0,QU=2.5)]교대조조[0(QL=0,QU=0)]명현증가(Z=-2.372,P=0.018),화종측험분수(2.63±0.65)교대조조(2.96±0.20)명현강저(t=-2.407,P=0.023).파금삼병조재식별고흥、비상、공구화분노음악시여대조조차이몰유통계학의의(균P＞0.05).파금삼병조식별고흥、비상음악정서득분이급총분균여련선시간존재명현상관성(r=-0.560、-0.572、-0.530,P=0.004、0.003、0.008),이여년령、병정、수교육시간、간역정신상태량표평분、UPDRSⅢ평분、H-Y분기、HAMA평분、HAMD평분、LDE、화종측험득분화음악배경균무명현상관성(균P ＞0.05).결론 본조파금삼병환자적음악정서인지미수손;음악정서인지여집행공능지간적관계상불학정.
Objective To investigate emotion recognition in music in patients with idiopathic Parkinson's disease (PD),and to further explore its relationship with executive function and related factors.Methods Twenty-four PD patients enrolled from the Department of Neurology,Beijing Hospital between January and June 2014 and 24 matched healthy controls were tested using 24 musical excerpts that expressed happiness,sadness,fear or anger.The two groups were tested for executive function using a simplified trail making test and a clock drawing test.All the patients were rated on the Hoehn-Yahr stage,the Unified Parkinson' s Disease Rating Scale (UPDRS) Ⅲ,the Hamilton Rating Scale for Anxiety (HAMA) and the Hamilton Rating Scale for Depression (HAMD).Results In trail making test,PD patients worked slower ((51.58 ±33.14) s) than controls ((34.46 ± 19.64) s) (t =2.178,P =0.036).PD patients got more errors (0 (QL =0,QU =2.5)) than controls (0 (QL =0,QU =0);Z=-2.372,P =0.018).In clock drawing test,PD patients got lower score (2.63 ±0.65) than controls (2.96 ±0.20)(t =-2.407,P =0.023).The difference between two groups was not statistically significant in the recognition of happy,sad,fear or anger music (all P ＞ 0.05).In PD group,the scores of the recognition of happy,sad music and the total score of musical emotion recognition were associated with the time of trail making test (r =-0.560,-0.572,-0.530,P =0.004,0.003,0.008),while not related to age,disease duration,education duration,the scores of Minimum Mental State Examination,the scores of UPDRS Ⅲ,Hoehn-Yahr stage,the scores of HAMA,the scores of HAMD,LDE,the scores of clock drawing test or musical background (all P ＞ 0.05).Conclusions PD patients are not impaired in emotion recognition in music in this study.The relationship between musical emotion recognition and executive function is unclear.