中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2015年
13期
59-61
,共3页
甘精胰岛素%二甲双胍缓释片%初诊2型糖尿病%系统性评价
甘精胰島素%二甲雙胍緩釋片%初診2型糖尿病%繫統性評價
감정이도소%이갑쌍고완석편%초진2형당뇨병%계통성평개
Glargine insulin%Metformin extended release tablets%Newly diagnosed type 2 diabetes%Systemic evaluation
目的：探讨联合应用甘精胰岛素与二甲双胍缓释片治疗初诊2型糖尿病的疗效。方法：病例资料来源于本社区2013年1月-12月诊治的初诊2型糖尿病患者65例。随机分成两组，对照组33例患者给予二甲双胍缓释片1片/d，同时每晚皮下注射诺和灵N；研究组32例患者给予二甲双胍缓释片1片/d，每晚皮下注射甘精胰岛素。对两组治疗前后空腹血糖（FBG），用餐2 h后血糖（PBG）及糖化血红蛋白（HbA1C）含量进行分析比较。结果：研究组治疗总有效率为90.9%，明显高于对照组71.9%，两组比较差异具有统计学意义（P<0.01）；研究组治疗后各项指标均有明显改善，两组比较差异均有统计学意义（P<0.05）。结论：联合应用甘精胰岛素与二甲双胍缓释片治疗初诊2型糖尿病疗效显著，有利于改善患者的症状，不但具有较好的降糖效果，且低血糖发生率更低，安全性好，值得推广及应用。
目的：探討聯閤應用甘精胰島素與二甲雙胍緩釋片治療初診2型糖尿病的療效。方法：病例資料來源于本社區2013年1月-12月診治的初診2型糖尿病患者65例。隨機分成兩組，對照組33例患者給予二甲雙胍緩釋片1片/d，同時每晚皮下註射諾和靈N；研究組32例患者給予二甲雙胍緩釋片1片/d，每晚皮下註射甘精胰島素。對兩組治療前後空腹血糖（FBG），用餐2 h後血糖（PBG）及糖化血紅蛋白（HbA1C）含量進行分析比較。結果：研究組治療總有效率為90.9%，明顯高于對照組71.9%，兩組比較差異具有統計學意義（P<0.01）；研究組治療後各項指標均有明顯改善，兩組比較差異均有統計學意義（P<0.05）。結論：聯閤應用甘精胰島素與二甲雙胍緩釋片治療初診2型糖尿病療效顯著，有利于改善患者的癥狀，不但具有較好的降糖效果，且低血糖髮生率更低，安全性好，值得推廣及應用。
목적：탐토연합응용감정이도소여이갑쌍고완석편치료초진2형당뇨병적료효。방법：병례자료래원우본사구2013년1월-12월진치적초진2형당뇨병환자65례。수궤분성량조，대조조33례환자급여이갑쌍고완석편1편/d，동시매만피하주사낙화령N；연구조32례환자급여이갑쌍고완석편1편/d，매만피하주사감정이도소。대량조치료전후공복혈당（FBG），용찬2 h후혈당（PBG）급당화혈홍단백（HbA1C）함량진행분석비교。결과：연구조치료총유효솔위90.9%，명현고우대조조71.9%，량조비교차이구유통계학의의（P<0.01）；연구조치료후각항지표균유명현개선，량조비교차이균유통계학의의（P<0.05）。결론：연합응용감정이도소여이갑쌍고완석편치료초진2형당뇨병료효현저，유리우개선환자적증상，불단구유교호적강당효과，차저혈당발생솔경저，안전성호，치득추엄급응용。
Objective:To explore the efficacy of the combination of glargine insulin and metformin extendedrelease tablets in the treatment of newly diagnosed type 2 diabetes. Method:65 patients with newly diagnosed type 2 diabetes were admitted in our community from January 2013 to December and were randomly divided into two groups,the control group was given a daily extended release metformin tablets and nightly subcutaneous Novolin N,the study group was given a daily extended release metformin tablets and nightly subcutaneous insulin glargine. Fasting blood glucose (FBG),two hours after meal blood glucose(PBG)and glycosylated hemoglobin(HbA1c)content of two groups before and after treatment were analyzed and compared.Result:The total efficiency rate of treatment of the study group was 90.9%, significantly higher than the control group of 71.9%,the difference was statistically significant(P<0.01);the indicators of the study group after treatment were significantly improved,and significantly than the control group the difference was statistically significant(P<0.05).Conclusion:The combination of glargine insulin and metformin extended release tablets in the treatment of newly diagnosed type 2 diabetic has efficacy significantly and helpful to improve the symptoms, not only has good hypoglycemic effect,and has a lower incidence of hypoglycemia,security is good,it is worthy promotion and application.
