中国现代医生
中國現代醫生
중국현대의생
CHINA MODERN DOCTOR
2015年
12期
74-77
,共4页
慢性宫颈炎%桂枝茯苓胶囊%头孢曲松钠%5％重铬酸钾溶液%血管内皮生长因子%自然杀伤T细胞
慢性宮頸炎%桂枝茯苓膠囊%頭孢麯鬆鈉%5％重鉻痠鉀溶液%血管內皮生長因子%自然殺傷T細胞
만성궁경염%계지복령효낭%두포곡송납%5％중락산갑용액%혈관내피생장인자%자연살상T세포
Chronic cervicitis%Guizhifuling capsule%Ceftriaxone sodium%5％ potassium dichromate solution%VEGF%NKTs
目的：比较头孢曲松钠联合5%重铬酸钾溶液与头孢曲松钠联合桂枝茯苓胶囊分别治疗慢性宫颈炎的临床疗效。方法103例慢性宫颈炎患者随机分为两组，两组均在头孢曲松钠1 g静脉滴注，1 g/(d·次)，连用7 d的基础上，对照组(50例)为头孢曲松钠联合5%重铬酸钾溶液局部治疗，每月治疗1次，连续2次为1个疗程；研究组(53例)为头孢曲松钠联合桂枝茯苓胶囊局部用药3 d上药1次，5次为1个疗程(15 d)，同时口服桂枝茯苓胶囊1次3粒，1天3次，连服15 d；两组均在3个月后观察临床疗效。观察VEGF与NKTs在两组患者血清中治疗前后的变化，并分析两者的相关性。结果对照组痊愈率42.0%，总有效率为76.0%；研究组痊愈率47.2%，总有效率为90.6%，两组有显著性差异(字2=3.96，P<0.05)。相关性分析显示VEGF与NKTs在不同慢性宫颈炎分级患者中呈正相关(P<0.05)。治疗后，两组患者 VEGF、NKTs较治疗前明显升高，且研究组明显高于对照组(P<0.05)。结论头孢曲松钠联合桂枝茯苓胶囊局部治疗慢性宫颈炎，同时口服桂枝茯苓胶囊疗效综合优于头孢曲松钠联合5%重铬酸钾溶液局部治疗。
目的：比較頭孢麯鬆鈉聯閤5%重鉻痠鉀溶液與頭孢麯鬆鈉聯閤桂枝茯苓膠囊分彆治療慢性宮頸炎的臨床療效。方法103例慢性宮頸炎患者隨機分為兩組，兩組均在頭孢麯鬆鈉1 g靜脈滴註，1 g/(d·次)，連用7 d的基礎上，對照組(50例)為頭孢麯鬆鈉聯閤5%重鉻痠鉀溶液跼部治療，每月治療1次，連續2次為1箇療程；研究組(53例)為頭孢麯鬆鈉聯閤桂枝茯苓膠囊跼部用藥3 d上藥1次，5次為1箇療程(15 d)，同時口服桂枝茯苓膠囊1次3粒，1天3次，連服15 d；兩組均在3箇月後觀察臨床療效。觀察VEGF與NKTs在兩組患者血清中治療前後的變化，併分析兩者的相關性。結果對照組痊愈率42.0%，總有效率為76.0%；研究組痊愈率47.2%，總有效率為90.6%，兩組有顯著性差異(字2=3.96，P<0.05)。相關性分析顯示VEGF與NKTs在不同慢性宮頸炎分級患者中呈正相關(P<0.05)。治療後，兩組患者 VEGF、NKTs較治療前明顯升高，且研究組明顯高于對照組(P<0.05)。結論頭孢麯鬆鈉聯閤桂枝茯苓膠囊跼部治療慢性宮頸炎，同時口服桂枝茯苓膠囊療效綜閤優于頭孢麯鬆鈉聯閤5%重鉻痠鉀溶液跼部治療。
목적：비교두포곡송납연합5%중락산갑용액여두포곡송납연합계지복령효낭분별치료만성궁경염적림상료효。방법103례만성궁경염환자수궤분위량조，량조균재두포곡송납1 g정맥적주，1 g/(d·차)，련용7 d적기출상，대조조(50례)위두포곡송납연합5%중락산갑용액국부치료，매월치료1차，련속2차위1개료정；연구조(53례)위두포곡송납연합계지복령효낭국부용약3 d상약1차，5차위1개료정(15 d)，동시구복계지복령효낭1차3립，1천3차，련복15 d；량조균재3개월후관찰림상료효。관찰VEGF여NKTs재량조환자혈청중치료전후적변화，병분석량자적상관성。결과대조조전유솔42.0%，총유효솔위76.0%；연구조전유솔47.2%，총유효솔위90.6%，량조유현저성차이(자2=3.96，P<0.05)。상관성분석현시VEGF여NKTs재불동만성궁경염분급환자중정정상관(P<0.05)。치료후，량조환자 VEGF、NKTs교치료전명현승고，차연구조명현고우대조조(P<0.05)。결론두포곡송납연합계지복령효낭국부치료만성궁경염，동시구복계지복령효낭료효종합우우두포곡송납연합5%중락산갑용액국부치료。
Objective To compare the clinical efficacy between ceftriaxone sodium combined with 5% potassium dichromate solution and ceftriaxone sodium combined with Guizhifuling capsule which treated the chroniccervicitis re-spectively. Methods A total of 103 cases of chronic cervicitis were randomly divided into two groups,both were in cef-triaxone sodium intravenous infusion,1g/day/time. On the basis of continuous intravenous injected for 7 days,the control group involved 50 patients treated with ceftriaxone sodium combined with 5% potassium dichromate solution, once a month,two consecutive times for a course of treatment. The study group(53 cases)was treated with ceftriaxone sodium combined with Guizhifuling capsule by local administration,3 days/times,5 times for 1 course of treatment (15 days). The clinical efficacy of the two groups was observed after 3 months. The change of VEGF and NKTs in both groups of patients before and after treatment was observed, and the correlations were further analyzed. Results The cure rate of the control group was 42.0%,the total effective rate was 76.0%;the cure rate of the research roup was 47.2%,the to-tal effective rate was 90.6%,the difference was significant (χ2=3.96,P<0.05). Correlation analysis showed that VEGF was positively correlated with NKTs in different classification of patients with chronic cervicitis (P<0.05). After treat-ment, VEGF and NKTs between the two groups increased significantly. Compared with the control group, and there were significant differences between the two groups (P<0.05). Conclusion The clinical efficacy of ceftriaxone sodium combined with Guizhifuling capsule in local treatment of chronic cervicitis is better than that of ceftriaxone sodium combined with 5%potassium dichromate solution.
