中国现代医生
中國現代醫生
중국현대의생
CHINA MODERN DOCTOR
2015年
12期
9-11,15
,共4页
鼻息肉%白介素-33%白介素-37%免疫组织化学
鼻息肉%白介素-33%白介素-37%免疫組織化學
비식육%백개소-33%백개소-37%면역조직화학
Nasal polyps%IL-33%IL-37%Immunohistochemical
目的：探讨白介素-33(IL-33)、白介素-37(IL-37)在鼻息肉中的表达及其在鼻息肉中发挥的作用。方法40例鼻息肉患者的鼻息肉组织及18例鼻中隔偏曲患者的正常鼻黏膜组织为本次研究对象，用免疫组织化学方法分别检测其中IL-33及IL-37的表达情况。结果鼻息肉组IL-33阳性率为65.0%，IL-37阳性率为20.0%。正常鼻黏膜组中IL-33阳性率为33.3%，IL-37阳性率为77.8%。结论 IL-33、IL37与鼻息肉发病密切相关。
目的：探討白介素-33(IL-33)、白介素-37(IL-37)在鼻息肉中的錶達及其在鼻息肉中髮揮的作用。方法40例鼻息肉患者的鼻息肉組織及18例鼻中隔偏麯患者的正常鼻黏膜組織為本次研究對象，用免疫組織化學方法分彆檢測其中IL-33及IL-37的錶達情況。結果鼻息肉組IL-33暘性率為65.0%，IL-37暘性率為20.0%。正常鼻黏膜組中IL-33暘性率為33.3%，IL-37暘性率為77.8%。結論 IL-33、IL37與鼻息肉髮病密切相關。
목적：탐토백개소-33(IL-33)、백개소-37(IL-37)재비식육중적표체급기재비식육중발휘적작용。방법40례비식육환자적비식육조직급18례비중격편곡환자적정상비점막조직위본차연구대상，용면역조직화학방법분별검측기중IL-33급IL-37적표체정황。결과비식육조IL-33양성솔위65.0%，IL-37양성솔위20.0%。정상비점막조중IL-33양성솔위33.3%，IL-37양성솔위77.8%。결론 IL-33、IL37여비식육발병밀절상관。
Objective To investigate the expression of IL-33,IL-37 in nasal polyps tissue,and their relevance to the pathogenesis of human nasal polyps. Methods Immunohistochemistry was used to detect the expression of IL-33,IL-37, in excisional nasal polyps tissue from 40 patients with nasal polyps. In addition,the expression of IL-33,IL-37 was also detected in normal nasal mucosa from 18 patients with the nasal septum deviation. Results In the nasal polyps tissues,IL-33 positive rate was 65.0%,IL-37 positive rate was 20.0%.In the normal nasal mucosa, IL-33 positive rate was 33.3%,IL-37 positive rate was 77.8%. Conclusion IL-33 and IL-37 play an important role in the pathogenesis of nasal polyps.
