中外医学研究
中外醫學研究
중외의학연구
CHINESE AND FOREIGN MEDICAL RESEARCH
2015年
14期
10-12
,共3页
小儿急性腹泻%细胞免疫%指标%意义
小兒急性腹瀉%細胞免疫%指標%意義
소인급성복사%세포면역%지표%의의
Acute diarrhoea in children%Cellular immunity%Index%Significance
目的：通过急性腹泻患儿服用布拉式酵母散剂，观察服用前后细胞免疫功能指标水平的变化情况及意义。方法：选取笔者所在医院2012年7月-2013年7月收治的200例急性腹泻患儿作为研究对象，按照随机数字表法将其分为观察组126例和对照组74例。观察组患儿在服用抗生素、蒙脱石散剂口服及补液的基础上加用布拉式酵母散剂进行治疗，对照组患儿仅服用抗生素、蒙脱石散剂口服及补液进行治疗，对两组的治疗效果、平均止泻时间进行对比分析，观察对细胞免疫功能指标水平的影响。结果：观察组患儿治疗后1个月的CD3、CD4和CD4/CD8均明显高于治疗前，CD8明显低于治疗前，差异均有统计学意义(P<0.05)，而对照组治疗前后比较差异均无统计学意义(P>0.05)。观察组的显效率66.67%和总有效率94.44%均明显高于对照组的33.78%和81.08%，差异均有统计学意义(P<0.05)。观察组的平均止泻时间(2.5±0.6)d明显短于对照组的(4.6±0.5)d，差异有统计学意义(t=25.3693，P=0.0000)。结论：在常规治疗的基础上加用布拉式酵母散剂对急性腹泻患儿进行治疗，可以增强小儿的细胞免疫功能，减少大便的次数，值得临床推广应用。
目的：通過急性腹瀉患兒服用佈拉式酵母散劑，觀察服用前後細胞免疫功能指標水平的變化情況及意義。方法：選取筆者所在醫院2012年7月-2013年7月收治的200例急性腹瀉患兒作為研究對象，按照隨機數字錶法將其分為觀察組126例和對照組74例。觀察組患兒在服用抗生素、矇脫石散劑口服及補液的基礎上加用佈拉式酵母散劑進行治療，對照組患兒僅服用抗生素、矇脫石散劑口服及補液進行治療，對兩組的治療效果、平均止瀉時間進行對比分析，觀察對細胞免疫功能指標水平的影響。結果：觀察組患兒治療後1箇月的CD3、CD4和CD4/CD8均明顯高于治療前，CD8明顯低于治療前，差異均有統計學意義(P<0.05)，而對照組治療前後比較差異均無統計學意義(P>0.05)。觀察組的顯效率66.67%和總有效率94.44%均明顯高于對照組的33.78%和81.08%，差異均有統計學意義(P<0.05)。觀察組的平均止瀉時間(2.5±0.6)d明顯短于對照組的(4.6±0.5)d，差異有統計學意義(t=25.3693，P=0.0000)。結論：在常規治療的基礎上加用佈拉式酵母散劑對急性腹瀉患兒進行治療，可以增彊小兒的細胞免疫功能，減少大便的次數，值得臨床推廣應用。
목적：통과급성복사환인복용포랍식효모산제，관찰복용전후세포면역공능지표수평적변화정황급의의。방법：선취필자소재의원2012년7월-2013년7월수치적200례급성복사환인작위연구대상，안조수궤수자표법장기분위관찰조126례화대조조74례。관찰조환인재복용항생소、몽탈석산제구복급보액적기출상가용포랍식효모산제진행치료，대조조환인부복용항생소、몽탈석산제구복급보액진행치료，대량조적치료효과、평균지사시간진행대비분석，관찰대세포면역공능지표수평적영향。결과：관찰조환인치료후1개월적CD3、CD4화CD4/CD8균명현고우치료전，CD8명현저우치료전，차이균유통계학의의(P<0.05)，이대조조치료전후비교차이균무통계학의의(P>0.05)。관찰조적현효솔66.67%화총유효솔94.44%균명현고우대조조적33.78%화81.08%，차이균유통계학의의(P<0.05)。관찰조적평균지사시간(2.5±0.6)d명현단우대조조적(4.6±0.5)d，차이유통계학의의(t=25.3693，P=0.0000)。결론：재상규치료적기출상가용포랍식효모산제대급성복사환인진행치료，가이증강소인적세포면역공능，감소대편적차수，치득림상추엄응용。
Objective:To observe the changes and significance of cell immune function index levels in children with acute diarrhea before and after taking Saccharomyces Boulardii Sachets.Method:200 cases of children with acute diarrhea admitted to our hospital were selected as the research objects,they were divided into the observation group for 126 cases and the control group for 74 cases according to the random number table method.The observation group was given antibiotics,oral rehydration of Smectite Powder treatment with Saccharomyces Boulardii Sachets,the control group was only given antibiotics,oral rehydration therapy and Smectite Powder.The treatment effect,average time of diarrhea between the two groups were compared and analyzed,and the effects on changes of cellular immune function index level were observed.Result:The CD3,CD4 and CD4/CD8 of the observation group after 1 month of treatment were significantly higher than the control group,the CD8 was significantly lower than the control group,the differences were statistically significant(P<0.05),the difference was not statistically significant before and after treatment in the control group(P>0.05).The significant efficiency and total effective rate of the observation group were 66.67%and 94.44%,which were significantly higher than 33.78%and 81.08%of the control group,the differences were statistically significant(P<0.05).The average time of diarrhea in the observation group was (2.5±0.6)d,which was significantly shorter than (4.6±0.5)d in the control group,the difference was statistically significant(t=25.3693,P=0.0000).Conclusion:On the basis of conventional treatment combined with Saccharomyces Boulardii Sachets in the treatment of children with acute diarrhea,can enhance the cellular immune function of children,reduce the number of bowel movements,is worthy of clinical application.
