中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2015年
14期
145-147
,共3页
危重患者%感染%降钙素原%诊断
危重患者%感染%降鈣素原%診斷
위중환자%감염%강개소원%진단
Critically ill patients%Infection%Procalcitonin%Diagnosis
目的：分析血清降钙素原（PCT）在危重患者感染诊断中的临床价值。方法：选择的研究对象为2011年7月-2014年7月本院收治的150例危重病患者，根据血液微生物培养结果分为感染组和非感染组，并同时测定两组患者的血清降钙素原和C反应蛋白（CRP），比较两种指标对危重患者感染早期诊断的特异性和敏感性。结果：感染组患者的CRP和PCT水平均明显高于非感染组，差异有统计学意义（P<0.01）。行CRP检测在诊断重症患者感染的特异性为20.37%（11/54），敏感性为64.58%（62/96）；行PCT检测在诊断重症患者感染的特异性为46.29%（25/54），敏感性为84.37%（81/96）；PCT检测早诊断危重患者的特异性与敏感性均高于CRP检测，差异均有统计学意义（P<0.05）。结论：血清PCT和CRP水平在危重患者发生感染时均出现增高，血清PCT检测在危重患者诊断其感染的敏感性和特异性均明显高于CRP检测，可以用于危重患者发生感染的早期诊断和治疗。
目的：分析血清降鈣素原（PCT）在危重患者感染診斷中的臨床價值。方法：選擇的研究對象為2011年7月-2014年7月本院收治的150例危重病患者，根據血液微生物培養結果分為感染組和非感染組，併同時測定兩組患者的血清降鈣素原和C反應蛋白（CRP），比較兩種指標對危重患者感染早期診斷的特異性和敏感性。結果：感染組患者的CRP和PCT水平均明顯高于非感染組，差異有統計學意義（P<0.01）。行CRP檢測在診斷重癥患者感染的特異性為20.37%（11/54），敏感性為64.58%（62/96）；行PCT檢測在診斷重癥患者感染的特異性為46.29%（25/54），敏感性為84.37%（81/96）；PCT檢測早診斷危重患者的特異性與敏感性均高于CRP檢測，差異均有統計學意義（P<0.05）。結論：血清PCT和CRP水平在危重患者髮生感染時均齣現增高，血清PCT檢測在危重患者診斷其感染的敏感性和特異性均明顯高于CRP檢測，可以用于危重患者髮生感染的早期診斷和治療。
목적：분석혈청강개소원（PCT）재위중환자감염진단중적림상개치。방법：선택적연구대상위2011년7월-2014년7월본원수치적150례위중병환자，근거혈액미생물배양결과분위감염조화비감염조，병동시측정량조환자적혈청강개소원화C반응단백（CRP），비교량충지표대위중환자감염조기진단적특이성화민감성。결과：감염조환자적CRP화PCT수평균명현고우비감염조，차이유통계학의의（P<0.01）。행CRP검측재진단중증환자감염적특이성위20.37%（11/54），민감성위64.58%（62/96）；행PCT검측재진단중증환자감염적특이성위46.29%（25/54），민감성위84.37%（81/96）；PCT검측조진단위중환자적특이성여민감성균고우CRP검측，차이균유통계학의의（P<0.05）。결론：혈청PCT화CRP수평재위중환자발생감염시균출현증고，혈청PCT검측재위중환자진단기감염적민감성화특이성균명현고우CRP검측，가이용우위중환자발생감염적조기진단화치료。
Objective: To analysis the clinical value of serum procalcitonin in critically ill patients’ infection diagnosis.Method:150 cases of critically ill patients were chose from July 2011 to July 2014 in our hospital, according to the results of microbiological culture of blood the patients were divided into infected group and non-infected group, patients’ serum procalcitonin and C-reactive protein at the same time were detected, the two indicators of infection in critically ill patients with early diagnostic specificity and sensitivity were compared.Result: The CRP and PCT levels of patients in infected group were significantly higher than non-infected group, the difference was statistically significant(P<0.01); CRP testing in the diagnosis of patients with severe infection, the specificity was 20.37% (11/54) and the sensitivity was 64.58%(62/96);PCT in the diagnosis of patients with severe infection, the specificity was 46.29%(25/54),and sensitivity was 84.37%(81/96); PCT detection and early diagnosis in critically ill patients of the specificity and sensitivity were higher than CRP testing, the difference was statistically significant(P<0.05). Conclusion:Serum PCT and CRP levels in critically ill patients all infected increased, serum PCT detect infection in critically ill patients with a diagnosis of sensitivity and specificity is significantly higher than CRP testing, it can be used for early diagnosis of infection in critically ill patients and treatment.
