CAJ | 학술논문

艰难梭菌是一种专性厌氧的革兰阳性芽孢杆菌,是抗生素相关性腹泻最常见的一种致病菌,可引起艰难梭菌相关性腹泻.近年来随着广谱抗生素的大量使用,菌株耐药性的增加,高毒力菌株的出现,艰难梭菌感染在全球的发生率明显上升.现就艰难梭菌相关性腹泻的研究进展作一简要综述.
간난사균시일충전성염양적혁란양성아포간균,시항생소상관성복사최상견적일충치병균,가인기간난사균상관성복사.근년래수착엄보항생소적대량사용,균주내약성적증가,고독력균주적출현,간난사균감염재전구적발생솔명현상승.현취간난사균상관성복사적연구진전작일간요종술.
Clostridium difficile is a gram-positive,obligate anaerobic bacillus,which is one of the most common pathogenic bacteria of antibiotic associated diarrhea,and can cause Clostridium difficile-associated diarrhea.In recent years,the incidence of Clostridium difficile infection has increased significantly in the world with the excessive use of broad-spectrum antibiotics,the increase of strains resistance,and the emergence of hypervirulent strains.This paper presents a brief review on research progress of Clostridium difficile-associated diarrhea.