CAJ | 학술논문

目的初步验证胃食管反流病问卷(GERD-Q)在婴幼儿胃食管反流病(GERD)辅助诊断中的价值.方法 2011年1月至2014年2月武汉市妇女儿童医疗保健中心门诊或住院部收治的有疑似GERD症状的婴儿148例、幼儿87例,均完成24 h食管pH值监测或上消化道碘水造影检查,任一项阳性即确定GERD的诊断,纳入GERD组,不符合者即纳入对照组.对所有患儿均完成GERD-Q量表调查.采用SPSS 17.0统计软件,率的比较用x2检验,组间评分比较用t检验.结果 1 ～11个月婴儿中,GERD组(111例)6个单项症状评分(ISS)均高于对照组(37例)(P＜0.05),GERD组综合症状评分(CSS)[(131.43±66.56)分]高于对照组[(33.70 ±40.03)分](t=8.42,P＜0.05).1～3岁幼儿中,GERD组(55例)6个单项症状ISS均高于对照组(32例)(P＜0.05),GERD组CSS[(98.58 ±66.75)分]高于对照组[(28.50±35.95)分](t=5.49,P＜0.05).结论年龄特异性GERD-Q对婴幼儿GERD症状筛选具有良好的关联度,适合用于对GERD进行评估.
목적 초보험증위식관반류병문권(GERD-Q)재영유인위식관반류병(GERD)보조진단중적개치.방법 2011년1월지2014년2월무한시부녀인동의료보건중심문진혹주원부수치적유의사GERD증상적영인148례、유인87례,균완성24 h식관pH치감측혹상소화도전수조영검사,임일항양성즉학정GERD적진단,납입GERD조,불부합자즉납입대조조.대소유환인균완성GERD-Q량표조사.채용SPSS 17.0통계연건,솔적비교용x2검험,조간평분비교용t검험.결과 1 ～11개월영인중,GERD조(111례)6개단항증상평분(ISS)균고우대조조(37례)(P＜0.05),GERD조종합증상평분(CSS)[(131.43±66.56)분]고우대조조[(33.70 ±40.03)분](t=8.42,P＜0.05).1～3세유인중,GERD조(55례)6개단항증상ISS균고우대조조(32례)(P＜0.05),GERD조CSS[(98.58 ±66.75)분]고우대조조[(28.50±35.95)분](t=5.49,P＜0.05).결론 년령특이성GERD-Q대영유인GERD증상사선구유량호적관련도,괄합용우대GERD진행평고.
Objective To preliminarily test the value of gastroesophageal reflux disease questionnaire (GERD-Q) in auxiliary diagnosis of gastroesophageal reflux disease(GERD) in infants and young children.Methods From January 2011 to February 2014,148 infants and 87 young children with suspected GERD symptoms were enrolled in the outpatient and inpatient departments of Wuhan Women and Children's Medical Care Center.The diagnosis of GERD were made through 24 h esophageal pH monitoring and upper gastrointestinal hysterosalpingography.Those with any examinations being positive were brought into GERD group,and the others into the control group.All cases had been surveyed with GERD-Q.Using SPSS17.0 statistical software,the ratio was compared with chi-square test,and the difference of the scores between groups with t test.Results In infants (1 to 11 months),the individual symptom scores (ISS) of the 6 symptoms in the GERD group (n =111) were all higher than those in the control group (37 cases) (P ＜ 0.05),and the composite and symptom scores (CSS) [(131.43 ± 66.56) scores] in the GERD group was higher than that [(33.70 ± 40.03) scores] in the control group (t =8.42,P ＜ 0.05).In young children (1 to 3 years old),the ISS in the GERD group(55 cases) were all higher than those in the control group(32 cases),and the CSS[(98.58 ± 66.75) scores] in the GERD group was also higher than that [(28.50 ± 35.95) scores] in the control group(t =5.49,P ＜ 0.05).Conclusions There is a good correlation for age-specific GERD-Q to distinguish GERD symptoms in infants and young children,which is suitable for the assessment of GERD.