CAJ | 학술논문

目的：探讨宫颈癌与正常宫颈、宫颈肌壁间肌瘤之间磁共振灌注加权成像(PWI)参数的差异。材料与方法通过磁共振灌注加权成像，获得32例宫颈癌患者与30例正常宫颈、30例宫颈肌壁间肌瘤患者的时间-信号强度曲线(TIC)、最大增强(ME)、首过最大灌注斜率(SSmax)、达峰时间(TTP)的数据，并进行对比分析，研究其灌注特性与血流动力学特征的相关性。结果宫颈癌组TIC曲线“速升平台”型25例，“速升缓降”型7例；正常组TIC曲线“缓慢上升”型22例，“速升平台”型8例；宫颈肌瘤组TIC曲线“速升平台”型24例，“缓慢上升”型6例。宫颈癌组的ME、SSmax、TTP与正常对照组的参数存在显著性差异(P＜0.001)，宫颈癌组与宫颈肌壁间肌瘤对照组各参数间亦存在显著性差异(P＜0.001)。结论 PWI能很好地反映宫颈癌血流动力学特征，有助于宫颈癌的鉴别诊断和临床治疗评估提供参考。
목적：탐토궁경암여정상궁경、궁경기벽간기류지간자공진관주가권성상(PWI)삼수적차이。재료여방법통과자공진관주가권성상，획득32례궁경암환자여30례정상궁경、30례궁경기벽간기류환자적시간-신호강도곡선(TIC)、최대증강(ME)、수과최대관주사솔(SSmax)、체봉시간(TTP)적수거，병진행대비분석，연구기관주특성여혈류동역학특정적상관성。결과궁경암조TIC곡선“속승평태”형25례，“속승완강”형7례；정상조TIC곡선“완만상승”형22례，“속승평태”형8례；궁경기류조TIC곡선“속승평태”형24례，“완만상승”형6례。궁경암조적ME、SSmax、TTP여정상대조조적삼수존재현저성차이(P＜0.001)，궁경암조여궁경기벽간기류대조조각삼수간역존재현저성차이(P＜0.001)。결론 PWI능흔호지반영궁경암혈류동역학특정，유조우궁경암적감별진단화림상치료평고제공삼고。
Objective: To explore the perfusion differences among cervical cancer, normal cervixand cervical intermural leiomyomas with magnetic resonance. Materials and Methods:We collected 32 cases of cervical cancer patients, 30 cases of normal cervix and 30 cases of patients with cervical intermural leiomyomas.Time signal-intensity curve (TIC), maximum enhancement (ME), steepest slope (SSmax), Time To Peak (TTP), were measured and analyzed on perfusion weighted imaging. Besides, the correlation between characteristics of perfusion and hemodynamic enhancement was calculated. Results:In the TIC type of cervical cancer group,"rapidly wash in followed by a plateau"had 25 cases,"rapidly wash in followed by a slowly wash out"had 7 cases;in the TIC type of normal cervix group,"slow wash in"had 22 cases,"rapidly wash in followed by a plateau"had 8 cases;in the TIC type of cervica intermural leiomyomas group,"rapidly wash infollowed by a plateau"had 24 cases,"slowly wash in " had 6 cases. there are great statistically signiifcant differences between ME, SSmax, TTP of the cervical cancer group and the normal cervix group (P<0.001);there are also great statistically signiifcant differences between cervical cancer group and cervical intermural leiomyomas group (P<0.001). Conclusions:PWI could relfect the hemodynamic characteristics of cervical cancer well,which could help with the differential diagnosis of cervical cancer,and provide the reference for the clinical evaluation.