国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2015年
10期
1377-1379
,共3页
胃肠道肿瘤%腹腔热灌注%化疗
胃腸道腫瘤%腹腔熱灌註%化療
위장도종류%복강열관주%화료
Gastrointestinal cancer%Intraperitoneal hyperthermic perfusion%Chemotherapy
目的 探讨胃肠道肿瘤患者采用腹腔热灌注化疗治疗的临床效果.方法 将本组纳入的85例患者根据随机数字表法随机分为观察组(n=43)和对照组(n=42).对照组单纯采用静脉化疗治疗,观察组在对照组基础上结合腹腔热灌注治疗.对比分析两组疗效、生存质量及毒副反应发生情况.结果 观察组总有效率明显高于对照组(65.12％ vs.40.48％,P＜0.05);观察组生存质量改善率显著高于对照组(44.19％ vs.19.05％,P＜0.05);两组毒副反应发生率比较差异无统计学意义(P＞0.05).结论 胃肠道肿瘤患者采用腹腔热灌注化疗治疗临床效果显著.
目的 探討胃腸道腫瘤患者採用腹腔熱灌註化療治療的臨床效果.方法 將本組納入的85例患者根據隨機數字錶法隨機分為觀察組(n=43)和對照組(n=42).對照組單純採用靜脈化療治療,觀察組在對照組基礎上結閤腹腔熱灌註治療.對比分析兩組療效、生存質量及毒副反應髮生情況.結果 觀察組總有效率明顯高于對照組(65.12％ vs.40.48％,P＜0.05);觀察組生存質量改善率顯著高于對照組(44.19％ vs.19.05％,P＜0.05);兩組毒副反應髮生率比較差異無統計學意義(P＞0.05).結論 胃腸道腫瘤患者採用腹腔熱灌註化療治療臨床效果顯著.
목적 탐토위장도종류환자채용복강열관주화료치료적림상효과.방법 장본조납입적85례환자근거수궤수자표법수궤분위관찰조(n=43)화대조조(n=42).대조조단순채용정맥화료치료,관찰조재대조조기출상결합복강열관주치료.대비분석량조료효、생존질량급독부반응발생정황.결과 관찰조총유효솔명현고우대조조(65.12％ vs.40.48％,P＜0.05);관찰조생존질량개선솔현저고우대조조(44.19％ vs.19.05％,P＜0.05);량조독부반응발생솔비교차이무통계학의의(P＞0.05).결론 위장도종류환자채용복강열관주화료치료림상효과현저.
Objective To investigate clinical effect of intraperitoneal hyperthermic perfusion chemotherapy in the treatment of gastrointestinal cancer.Methods 85 cases of gastrointestinal cancer were divided into observation group (n=43) and control group (n=42) according to random number table.Control group was treated with intravenous chemotherapy treatment,observation group was treated with intraperitoneal hyperthermic perfusion on the basis of control group.Compared clinical efficacy,quality of life and toxic side effects of two groups.Results The total effective rate of observation group was significantly higher than that of control group (65.12％ vs.40.48％,P＜0.05);the improvement rate of QOL of observation group was significantly higher than that of control group (44.19％ vs.19.05％,P＜0.05);there was no statistically significant difference in the incidence of toxic side effects between two groups (P＞0.05).Conclusion Intraperitoneal hyperthermic perfusion chemotherapy in the treatment of gastrointestinal cancer has significant clinical effect.
