中国医药
中國醫藥
중국의약
CHINA MEDICINE
2015年
5期
619-622
,共4页
稳定型冠心病%左心室收缩功能%中西医结合
穩定型冠心病%左心室收縮功能%中西醫結閤
은정형관심병%좌심실수축공능%중서의결합
Stable coronary artery disease%Left ventricular systolic function%Integrated traditional Chinese and western medicine
目的 观察中西医结合治疗对稳定型冠状动脉粥样硬化性心脏病(冠心病)患者左心室收缩功能的改善及对血压、心率等指标的影响.方法 纳入2013年1-10月就诊于首都医科大学附属北京安贞医院的慢性稳定型冠心病患者30例.根据配对原则分为西药常规治疗组和中西医结合治疗组,各15例.西药常规治疗组患者按照指南采用西药常规治疗;中西医结合治疗组在西药常规治疗组治疗方案的基础上加用活心丸,3丸/d,口服.治疗8周后,比较2组患者治疗前后左心室收缩功能与血压、心率等指标的变化情况.结果 西药常规治疗组收缩压、舒张压、心率、左心室射血分数(LVEF)、左心室短轴缩短分数(LVFS)治疗前后比较[(134±14) mmHg(1 mmHg =0.133 kPa)比(129±11) mmHg,(80±9)mmHg比(73±12) mmHg,(66±5)次/min比(65±9)次/min,(61±8)％比(62±5)％,(35±7)％比(36±10)％],差异无统计学意义(P＞0.05).中西医结合治疗组收缩压、舒张压、心率、LVEF、LVFS治疗前后比较[(132±14) mmHg比(110±9)mmHg,(76±11)mmHg比(70±8)mmHg,(65±7)次/min比(60±5)次/min,(59±7)％比(65±10)％,(32±5)％比(37±8)％],差异均有统计学意义(均P＜0.05);中西医结合治疗组的心率、收缩压比西药常规治疗组降低更明显,LVEF和LVFS比西药常规治疗组升高更明显,差异有统计学意义(P＜0.05).结论 中西医结合治疗可能具有改善稳定型冠心病患者左心室收缩功能的作用.
目的 觀察中西醫結閤治療對穩定型冠狀動脈粥樣硬化性心髒病(冠心病)患者左心室收縮功能的改善及對血壓、心率等指標的影響.方法 納入2013年1-10月就診于首都醫科大學附屬北京安貞醫院的慢性穩定型冠心病患者30例.根據配對原則分為西藥常規治療組和中西醫結閤治療組,各15例.西藥常規治療組患者按照指南採用西藥常規治療;中西醫結閤治療組在西藥常規治療組治療方案的基礎上加用活心汍,3汍/d,口服.治療8週後,比較2組患者治療前後左心室收縮功能與血壓、心率等指標的變化情況.結果 西藥常規治療組收縮壓、舒張壓、心率、左心室射血分數(LVEF)、左心室短軸縮短分數(LVFS)治療前後比較[(134±14) mmHg(1 mmHg =0.133 kPa)比(129±11) mmHg,(80±9)mmHg比(73±12) mmHg,(66±5)次/min比(65±9)次/min,(61±8)％比(62±5)％,(35±7)％比(36±10)％],差異無統計學意義(P＞0.05).中西醫結閤治療組收縮壓、舒張壓、心率、LVEF、LVFS治療前後比較[(132±14) mmHg比(110±9)mmHg,(76±11)mmHg比(70±8)mmHg,(65±7)次/min比(60±5)次/min,(59±7)％比(65±10)％,(32±5)％比(37±8)％],差異均有統計學意義(均P＜0.05);中西醫結閤治療組的心率、收縮壓比西藥常規治療組降低更明顯,LVEF和LVFS比西藥常規治療組升高更明顯,差異有統計學意義(P＜0.05).結論 中西醫結閤治療可能具有改善穩定型冠心病患者左心室收縮功能的作用.
목적 관찰중서의결합치료대은정형관상동맥죽양경화성심장병(관심병)환자좌심실수축공능적개선급대혈압、심솔등지표적영향.방법 납입2013년1-10월취진우수도의과대학부속북경안정의원적만성은정형관심병환자30례.근거배대원칙분위서약상규치료조화중서의결합치료조,각15례.서약상규치료조환자안조지남채용서약상규치료;중서의결합치료조재서약상규치료조치료방안적기출상가용활심환,3환/d,구복.치료8주후,비교2조환자치료전후좌심실수축공능여혈압、심솔등지표적변화정황.결과 서약상규치료조수축압、서장압、심솔、좌심실사혈분수(LVEF)、좌심실단축축단분수(LVFS)치료전후비교[(134±14) mmHg(1 mmHg =0.133 kPa)비(129±11) mmHg,(80±9)mmHg비(73±12) mmHg,(66±5)차/min비(65±9)차/min,(61±8)％비(62±5)％,(35±7)％비(36±10)％],차이무통계학의의(P＞0.05).중서의결합치료조수축압、서장압、심솔、LVEF、LVFS치료전후비교[(132±14) mmHg비(110±9)mmHg,(76±11)mmHg비(70±8)mmHg,(65±7)차/min비(60±5)차/min,(59±7)％비(65±10)％,(32±5)％비(37±8)％],차이균유통계학의의(균P＜0.05);중서의결합치료조적심솔、수축압비서약상규치료조강저경명현,LVEF화LVFS비서약상규치료조승고경명현,차이유통계학의의(P＜0.05).결론 중서의결합치료가능구유개선은정형관심병환자좌심실수축공능적작용.
Objective To observe the effect of integrated traditional Chinese and western medicine in improvement of left ventricular systolic function in patients with stable coronary artery disease.Methods Totally 30 cases of patients with coronary heart disease were enrolled and divided into integrated traditional Chinese and western medicine group (15 cases) and conventional western medicine group (15 cases).The patients were given conventional western medicine according the guideline in conventional western medicine group,and were given Huoxin pills plus routine treatment in integrated traditional Chinese and western medicine group.After 8 weeks of treatment,the changes of blood pressure,heart rate,left ventricular ejection fraction (LVEF) and left ventricular fractional shortening (LVFS) were measured and compared between the two groups.Results Before and after treatment,the systolic pressure,diastolic pressure,heart rate,LVEF and LVFS were (134±13) mmHg and (129 ± 119) mmHg,(80 ±9) mmHg and (73 ± 12) mmHg,(66 ±5) times/min and (65 ±9) times/min,(61 ±8)％ and (62 ±5)％,(35 ±7)％ and (36 ± 10)％ in conventional western medicine group,(132 ± 14) mmHg and (110 ±9) mmHg,(76 ± 11) mmHg and (70 ±8)mmHg,(65 ±7) times/min and (60 ±5) times/min,(59 ± 7)％ and (65 ± 10)％,(32 ± 5)％ and (37 ± 8)％ in integrated traditional Chinese and western medicine group,respectively.The systolic pressure,diastolic pressure,heart rate,LVEF and LVFS were all statistically improved after treatment in integrated traditional Chinese and western medicine group (all P ＜ 0.05);while only the diastolic blood pressure was significantly reduced after treatment in conventional western medicine group (P ＜ 0.05),the other indicators were not statistically improved (all P ＞ 0.05).The systolic pressure and heart rate were more reduced,the LVEF and LVFS were more increase in integrated traditional Chinese and western medicine group compared with conventional western medicine group (all P ＜ 0.05).Conclusion Integrated traditional Chinese and western medicine may improve the left ventricular systolic function in patients with stable coronary artery disease.
