中华神经科杂志
中華神經科雜誌
중화신경과잡지
Chinese Journal of Neurology
2015年
4期
298-301
,共4页
肯尼迪病%评估%量表%信度%效度
肯尼迪病%評估%量錶%信度%效度
긍니적병%평고%량표%신도%효도
Kennedy's disease%Assessment%Scale%Reliability%Validity
目的 根据肯尼迪病患者的临床特点,设计一种针对肯尼迪病患者的临床评估量表,并初步验证量表的信度和效度.方法 在肌萎缩侧索硬化功能等级量表的基础上设计出“肯尼迪病1234量表”,对2009年6月至2014年3月在北京大学第三医院神经科门诊或病房就诊的81例基因确诊的肯尼迪病患者进行“肯尼迪病1234量表”评分,进而检验“肯尼迪病1234量表”的信度和效度.采用Cronbach's α系数和分半信度检验量表的信度,效度检验采用内容效度和结构效度.结果 总量表的Cronbach'sα系数为0.789,分半信度为0.868;呼吸与总分的相关系数0.3～0.4,语言、吞咽、书写与总分的相关系数为0.4～0.5,流涎、切分食物及手持器皿、穿衣和个人卫生、卧床和调整被褥、行走、上楼梯6项条目与总分的相关系数均大于0.5(P ＜0.01);探索性因素分析提取的4个公因子符合量表编制的理论结构,各条目在其公因子的负荷值为0.541 ～0.864;量表评分与患者病程的回归系数为-0.274,随着病程的延长,总分逐渐降低.结论 “肯尼迪病1234量表”设计简便、易操作,具有良好的信度和效度,与病程具有相关性,可较好地对肯尼迪病患者的病情进行定量评价,为临床研究提供服务.
目的 根據肯尼迪病患者的臨床特點,設計一種針對肯尼迪病患者的臨床評估量錶,併初步驗證量錶的信度和效度.方法 在肌萎縮側索硬化功能等級量錶的基礎上設計齣“肯尼迪病1234量錶”,對2009年6月至2014年3月在北京大學第三醫院神經科門診或病房就診的81例基因確診的肯尼迪病患者進行“肯尼迪病1234量錶”評分,進而檢驗“肯尼迪病1234量錶”的信度和效度.採用Cronbach's α繫數和分半信度檢驗量錶的信度,效度檢驗採用內容效度和結構效度.結果 總量錶的Cronbach'sα繫數為0.789,分半信度為0.868;呼吸與總分的相關繫數0.3～0.4,語言、吞嚥、書寫與總分的相關繫數為0.4～0.5,流涎、切分食物及手持器皿、穿衣和箇人衛生、臥床和調整被褥、行走、上樓梯6項條目與總分的相關繫數均大于0.5(P ＜0.01);探索性因素分析提取的4箇公因子符閤量錶編製的理論結構,各條目在其公因子的負荷值為0.541 ～0.864;量錶評分與患者病程的迴歸繫數為-0.274,隨著病程的延長,總分逐漸降低.結論 “肯尼迪病1234量錶”設計簡便、易操作,具有良好的信度和效度,與病程具有相關性,可較好地對肯尼迪病患者的病情進行定量評價,為臨床研究提供服務.
목적 근거긍니적병환자적림상특점,설계일충침대긍니적병환자적림상평고량표,병초보험증량표적신도화효도.방법 재기위축측색경화공능등급량표적기출상설계출“긍니적병1234량표”,대2009년6월지2014년3월재북경대학제삼의원신경과문진혹병방취진적81례기인학진적긍니적병환자진행“긍니적병1234량표”평분,진이검험“긍니적병1234량표”적신도화효도.채용Cronbach's α계수화분반신도검험량표적신도,효도검험채용내용효도화결구효도.결과 총량표적Cronbach'sα계수위0.789,분반신도위0.868;호흡여총분적상관계수0.3～0.4,어언、탄인、서사여총분적상관계수위0.4～0.5,류연、절분식물급수지기명、천의화개인위생、와상화조정피욕、행주、상루제6항조목여총분적상관계수균대우0.5(P ＜0.01);탐색성인소분석제취적4개공인자부합량표편제적이론결구,각조목재기공인자적부하치위0.541 ～0.864;량표평분여환자병정적회귀계수위-0.274,수착병정적연장,총분축점강저.결론 “긍니적병1234량표”설계간편、역조작,구유량호적신도화효도,여병정구유상관성,가교호지대긍니적병환자적병정진행정량평개,위림상연구제공복무.
Objective To develop a scale to assess Kennedy's disease (KD) based on patients' clinical characteristics and to validate its application in patients.Methods We developed KD1234 Scale following the model of Amyotrophic Lateral Sclerosis-Functional Rating Scale.Using this new scale,we assessed patients with genetic diagnosis of KD and evaluated the reliability and validity of the new scale.Reliability was analyzed using Cronbach' s α coefficient and split-half reliability.Validity was analyzed by content validity and structure validity.Results The Cronbach' s α coefficient of the total scale was 0.789 and split-half reliability coefficient was 0.868.The α of breathing with total score was 0.3-0.4,α of written,language and swallowing with the total score was 0.4-0.5,α of other items with the total score was ＞ 0.5 (P ＜ 0.01 in each of above α).Four common factors extracted by exploratory factor analysis had well correspondence between the scale construction and the theoretical construction.Factor loading was ranged from 0.541 to 0.864 for each item.The duration of the disease showed some correlation with the score of KD1234 Scale.Conclusions The KD1234 Scale demonstrates high reliability and validity.The duration of the disease indicates negative correlation with KD1234 Scale scores.The KD1234 Scale can be used in clinical research to evaluate the condition of KD patients quantitatively.
