CAJ | 학술논문

目的了解鲍曼不动杆菌感染现状，分析其耐药谱变迁，动态监测其耐药性及其发展趋势，为临床各科室控制感染及合理应用抗菌药物提供依据。方法用VITEK2鉴定系统对菌株进行鉴定及药敏试验。用WHONET5.5软件对药敏结果进行统计学分析。结果分离出鲍曼不动杆菌405株，其检出率以重症监护室、呼吸科的居多，分别为20.5%、10.6%。其次是泌尿外科、神经外科、乳腺烧伤外科及皮肤痔瘘科。2012~2013年所监测抗生素的耐药性有逐步升高的趋势，尤以2013年上升更为显著，特别是鲍曼不动杆菌对碳青霉烯类耐药率增加迅速，重症监护室病房鲍曼不动杆菌对亚胺培南耐药率达80.1%。结论鲍曼不动杆菌耐药性日趋严重，应引起临床科室以及医院感染科室的高度重视。
목적료해포만불동간균감염현상，분석기내약보변천，동태감측기내약성급기발전추세，위림상각과실공제감염급합리응용항균약물제공의거。방법용VITEK2감정계통대균주진행감정급약민시험。용WHONET5.5연건대약민결과진행통계학분석。결과분리출포만불동간균405주，기검출솔이중증감호실、호흡과적거다，분별위20.5%、10.6%。기차시비뇨외과、신경외과、유선소상외과급피부치루과。2012~2013년소감측항생소적내약성유축보승고적추세，우이2013년상승경위현저，특별시포만불동간균대탄청매희류내약솔증가신속，중증감호실병방포만불동간균대아알배남내약솔체80.1%。결론포만불동간균내약성일추엄중，응인기림상과실이급의원감염과실적고도중시。
Objective Understanding of acinetobacter baumanni infection status, analyze the changes of drug resistance of dynamic monitoring the drug resistance and developing trend of clinical infection control department and provide evidence for reasonable application of antimicrobial agents.Methods With VITEK2 identification system for identification and drug sensitive test strains.With WHONET5.5 software with the result of drug susceptibility for statistical analysis.Results Isolated 405 strains of acinetobacter baumanni , the detection rate in the majority with intensive care unit, respiratory, 20.5%, 10.6%respectively. Secondly, urology, neurosurgery, breast burn surgery and skin division.2012~2012 monitoring antibiotic resistance has a tendency to escalate, especial y in the rising more dramatical y in 2013, especial y the acinetobacter baumanni on carbon penicil ium alkene antimicrobial increase rapidly, the intensive care unit ward acinetobacter baumanni to imine culture south resistant rate of 80.1.Conclusion Acinetobacter baumanni resistance has become increasingly serious, should cause clinical departments and hospital infection department at aches great importance to.