CAJ | 학술논문

目的通过监测住院患者感染病原菌分布及耐药特征，及时掌握医院耐药菌监测情况，指导临床合理应用抗菌药物。方法采用法国梅里埃微生物API软件鉴定系统及ATB药敏测试板同时对精神病专科医院2013年1月~2014年6月临床各科送检的标本进行菌株鉴定与药物敏感性试验检测，用WHONET5软件进行统计分析。结果共分离出282株病原菌，其中，革兰氏阴性菌150株占53.19%，革兰氏阳性菌117株占41.49%，真菌15株占5.32%。产ESBLs的大肠埃希菌，肺炎克雷伯菌对哌拉西林/三唑巴坦和碳青霉烯类敏感，MARS和MRCNS对夫西地酸、呋喃妥因、万古霉素均较敏感。结论医院应及时监测细菌耐药性情况，临床应重视病原菌检查及根据药敏合理选择应用抗菌药物，减少病原菌耐药的发生。
목적통과감측주원환자감염병원균분포급내약특정，급시장악의원내약균감측정황，지도림상합리응용항균약물。방법채용법국매리애미생물API연건감정계통급ATB약민측시판동시대정신병전과의원2013년1월~2014년6월림상각과송검적표본진행균주감정여약물민감성시험검측，용WHONET5연건진행통계분석。결과공분리출282주병원균，기중，혁란씨음성균150주점53.19%，혁란씨양성균117주점41.49%，진균15주점5.32%。산ESBLs적대장애희균，폐염극뢰백균대고랍서림/삼서파탄화탄청매희류민감，MARS화MRCNS대부서지산、부남타인、만고매소균교민감。결론의원응급시감측세균내약성정황，림상응중시병원균검사급근거약민합리선택응용항균약물，감소병원균내약적발생。
Objective According to analysis the distribution and drug resistance of pathogenic bacteria in Hospitalized patients,grasp the Monitoring situation of the Drug-resistant bacteria in hospital,guide pharmacists clinical rational administration.Methods By using method of The French bioMerieux microorganism API software evaluation system and ATB drug sensitive test,identified the strain and tested the drug sensitivity-al clinical samples (the psychiatric hospital from January 2012 to December 2013 year),used WHONET5 software for statistical analysis.Results A total of 282 strains of pathogens has isolated,.The 150 strains of gram negative bacteria accounted for 53.19%,117 gram positive bacteria accounted for 41.49%,15 strains of fungi accounted for 5.32%.ESBLs of Escherichia coli,ESBLs of Escherichia coli were sensitive to piperacil in,three tazobactam,carbopenems,MARS,MRCNS were sensitive to Fusidic acid,nitrofurantoin,vancomycin. Conclusion The hospital should be timely monitoring of bacterial drug resistance,clinical at ention should be paid to pathogenic bacteria and drug sensitivity test,according to the reasonable application of antibiotics,reduce the incidence of bacterial resistance.