CAJ | 학술논문

目的评价深度水解蛋白配方奶配合早期微量喂养在极低出生体重儿营养支持中的临床应用效果.方法选取2013年1月至2014年11月出生12小时内人住惠东县妇幼保健院新生儿科的极低出生体重儿90例,按抽签法随机分为A、B、C组.A组:12小时内给予深度水解蛋白配方奶(eHF)微量喂养,14天后改等量的早产儿配方奶(SPF)继续喂养;B组:12小时内给予SPF微量喂养;C组:为对照组,给予常规治疗,12小时以后开始SPF喂养.比较三组患儿恢复出生体重的日龄、喂养不耐受的发生率及新生儿贫血、宫外发育迟缓和NEC的发生率.结果恢复出生体重时间A组短于B、C组,喂养不耐受发生率A组低于B组、C组,差异均有统计学意义;三组喂养方式下,A组新生儿贫血、宫外发育迟缓和NEC发生率低于B组和C组.结论深度水解蛋白配方奶配合早期微量喂养可促进极低出生体重儿体重的早期恢复,改善喂养不耐受的发生率.
목적 평개심도수해단백배방내배합조기미량위양재겁저출생체중인영양지지중적림상응용효과.방법 선취2013년1월지2014년11월출생12소시내인주혜동현부유보건원신생인과적겁저출생체중인90례,안추첨법수궤분위A、B、C조.A조:12소시내급여심도수해단백배방내(eHF)미량위양,14천후개등량적조산인배방내(SPF)계속위양;B조:12소시내급여SPF미량위양;C조:위대조조,급여상규치료,12소시이후개시SPF위양.비교삼조환인회복출생체중적일령、위양불내수적발생솔급신생인빈혈、궁외발육지완화NEC적발생솔.결과 회복출생체중시간A조단우B、C조,위양불내수발생솔A조저우B조、C조,차이균유통계학의의;삼조위양방식하,A조신생인빈혈、궁외발육지완화NEC발생솔저우B조화C조.결론 심도수해단백배방내배합조기미량위양가촉진겁저출생체중인체중적조기회복,개선위양불내수적발생솔.
Objective To evaluate the clinical efficacy of minimal enteral feeding of extensively hydrolyzed infant formula in nutritional support for very low birth weight infants.Methods 90 very low birth weight infants born within 12 hours and admitted into Department of Neonates,Huidong Children and Maternal Hospital from January 2013,to November,2014 were selected and were randomly divided into group A,group B,and group C according to lottery method.Group A were minimally fed with extensively hydrolyzed infant formula (eHF) within 12 hours,14 days from then with the same amount of standard preterm infant formula (SPF);group B with SPF within 12 hours;and group C (a control group) conventionally treated and with SPF 12 hours after being admitted.The time recovering to birth weight and the incidences of feeding intolerance,anemia,extra uterine growth restriction (EUGR),and necrotizing enterocolitis (NEC).Results The time recovering to birth weight was significantly shorter and the incidence of feeding intolerance was lower in group A than in group B and group C,with statistical differences.The incidences of anemia,EUGR,and NEC were lower in group A than in group B and group C.Conclusions Minimal enteral feeding of extensively hydrolyzed infant formula with can recover very low birth weight infants' weight early and decrease the incidence of feeding intolerance.