CAJ | 학술논문

目的：应用自体骨髓经皮注射移植的方法治疗骨不连和骨折延迟愈合，并观察其治疗效果。方法2001至2011年，选择不同部位骨不连、骨折延迟愈合患者36例，在无菌条件下行自体髂骨骨髓穿刺抽吸，X线引导下，经皮注射移植到患部，并配合外固定等治疗。每部位注射2～3次，平均2．4次。每3～4周注射1次。结果术后平均随访患者9个月。36例患者中，32例治愈，4例失败而选择其他治疗方法，无感染及并发症发生。结论自体骨髓经皮注射移植是一种效果确切、简便易行、省钱微创、尤其在患者全身或局部条件不宜复杂操作时更彰显优势的治疗骨不连和骨折迟缓愈合的实用治疗方法。
목적：응용자체골수경피주사이식적방법치료골불련화골절연지유합，병관찰기치료효과。방법2001지2011년，선택불동부위골불련、골절연지유합환자36례，재무균조건하행자체가골골수천자추흡，X선인도하，경피주사이식도환부，병배합외고정등치료。매부위주사2～3차，평균2．4차。매3～4주주사1차。결과술후평균수방환자9개월。36례환자중，32례치유，4례실패이선택기타치료방법，무감염급병발증발생。결론자체골수경피주사이식시일충효과학절、간편역행、성전미창、우기재환자전신혹국부조건불의복잡조작시경창현우세적치료골불련화골절지완유합적실용치료방법。
Objective To observe the application of percutaneous autogenous bone marrow injection graft -ing for management of 3 6 cases with delayed union or nonunion of fractures .Methods In the period from 2 0 0 1 to 2 0 1 1 ,3 6 patients with delayed and non -union of long bones were selected for bone marrow injection .The <br> procedures were done in the operative theatre in which the bone marrow were aspirated from the anterior or pos-terior iliac crest and injected into the fracture site under fluoroscopic control .At a dose of 5 ~2 0 ml the optimal injection interval was 3 ~4 weeks and the injection required 2 ~3 times .Results During a mean follow up of 9 months ,3 2 of the 3 6 cases healed with the technique of marrow injection .The time to clinical and roentgen graphic union was 6 ~1 1 months after injection (averaged 9 months) .4 cases failed to choose other treatments , no infection and complications .Conclusion Bone marrow injection is as effective as past open autologous graft-ing but with considerably fewer disadvantages and also it is a relatively simple technique ,especially for elderly and infirm patients .