国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2015年
9期
1250-1252
,共3页
双水平无创正压通气%呼吸衰竭%慢性肺源性心脏病%血液N端脑钠肽前体
雙水平無創正壓通氣%呼吸衰竭%慢性肺源性心髒病%血液N耑腦鈉肽前體
쌍수평무창정압통기%호흡쇠갈%만성폐원성심장병%혈액N단뇌납태전체
BiPAP%Respiratory failure%Chronic pulmonary heart disease%NT-proBNP
目的 探讨双水平气道正压无创通气(BiPAP)对呼吸衰竭并慢性肺源性心脏病临床治疗效果.方法 选择2012年1月至2014年10月我科收治的65例呼吸衰竭并慢性肺心病(失代偿期)患者,随机分为两组,对照组32例,观察组33例.对照组给予常规对症治疗,观察组在常规对症治疗基础上加用BiPAP无创通气治疗,观察两组患者治疗前及治疗后6、24、48 h心率(HR)、呼吸频率(R)、血气分析指标(PaCO2、PaO2)及血液N端脑钠肽前体(NT-proBNP)水平.结果 观察组治疗6h后,患者心率、呼吸频率、血气分析指标改善较对照组差异有统计学意义(P＜0.05),治疗48 h后观察组NT-proBNP下降较对照组差异有统计学意义(P＜0.05).结论 采用BiPAP无创通气治疗呼吸衰竭并慢性肺源性心脏病患者,可有效改善临床症状、血气分析、心衰指标,纠正呼吸衰竭、心力衰竭,值得临床推广应用.
目的 探討雙水平氣道正壓無創通氣(BiPAP)對呼吸衰竭併慢性肺源性心髒病臨床治療效果.方法 選擇2012年1月至2014年10月我科收治的65例呼吸衰竭併慢性肺心病(失代償期)患者,隨機分為兩組,對照組32例,觀察組33例.對照組給予常規對癥治療,觀察組在常規對癥治療基礎上加用BiPAP無創通氣治療,觀察兩組患者治療前及治療後6、24、48 h心率(HR)、呼吸頻率(R)、血氣分析指標(PaCO2、PaO2)及血液N耑腦鈉肽前體(NT-proBNP)水平.結果 觀察組治療6h後,患者心率、呼吸頻率、血氣分析指標改善較對照組差異有統計學意義(P＜0.05),治療48 h後觀察組NT-proBNP下降較對照組差異有統計學意義(P＜0.05).結論 採用BiPAP無創通氣治療呼吸衰竭併慢性肺源性心髒病患者,可有效改善臨床癥狀、血氣分析、心衰指標,糾正呼吸衰竭、心力衰竭,值得臨床推廣應用.
목적 탐토쌍수평기도정압무창통기(BiPAP)대호흡쇠갈병만성폐원성심장병림상치료효과.방법 선택2012년1월지2014년10월아과수치적65례호흡쇠갈병만성폐심병(실대상기)환자,수궤분위량조,대조조32례,관찰조33례.대조조급여상규대증치료,관찰조재상규대증치료기출상가용BiPAP무창통기치료,관찰량조환자치료전급치료후6、24、48 h심솔(HR)、호흡빈솔(R)、혈기분석지표(PaCO2、PaO2)급혈액N단뇌납태전체(NT-proBNP)수평.결과 관찰조치료6h후,환자심솔、호흡빈솔、혈기분석지표개선교대조조차이유통계학의의(P＜0.05),치료48 h후관찰조NT-proBNP하강교대조조차이유통계학의의(P＜0.05).결론 채용BiPAP무창통기치료호흡쇠갈병만성폐원성심장병환자,가유효개선림상증상、혈기분석、심쇠지표,규정호흡쇠갈、심력쇠갈,치득림상추엄응용.
Objective To study the therapeutic effect of bilevel positive airway pressure noninvasive ventilation (BiPAP) on respiratory failure complicated with chronic pulmonary heart disease.Methods 65 patient with respiratory failure complicated with chronic pulmonary heart disease patients admitted into our department from January,2012 to October,2014 were randomly divided into a control group (n=32) and an observation group (n=33).The control group were given routine symptomatic treatment.In addition,the observation group were treated with BiPAP.Before and 6,24,and 48 hours after the treatment,the heart rate(HR),respiratory frequency (R),blood gas analysis indexes (PaCO2 and PaO2),and blood level fo NT-proBNP of both groups were observed.Results 6 hours after the treatment,the HR,R,PaCO2,and PaO2,were better in the observation group than in the control group,with statistical differences (P＜0.05).48 hours after the treatment,the serum level of NT-proBNP decreased more obviously in the observation group than in the control group,with a statistical difference (P＜0.05).Conclusions BiPAP is an effective ventilation pattern for respiratory failure complicated with chronic pulmonary heart disease,can effectively improve the clinical symptoms,blood gas analysis,and hart failure indicators,and is worth being clinically generalized.
