中国现代药物应用
中國現代藥物應用
중국현대약물응용
CHINESE JOURNAL OF MODERN DRUG APPLICATION
2015年
10期
237-239,240
,共4页
妊娠期糖尿病%基层医院%筛查%管理
妊娠期糖尿病%基層醫院%篩查%管理
임신기당뇨병%기층의원%사사%관리
Gestational diabetes mellitus%Primary hospital%Screening%Management
目的：探讨基层医院妊娠期糖尿病(GDM)的筛查和管理模式。方法98例GDM产妇为研究对象(观察组)；选择同期糖耐量筛查正常的200例产妇为对照组。对GDM产妇实施基层医院GDM管理模式。统计GDM产妇的一般资料。对GDM相关危险因素进行多因素Logistic回归分析。比较观察组和对照组产妇和围生儿围生期并发症。结果≥35岁[OR=1.1601,95%CI(1.051,1.310)]、有糖尿病家族史[OR=3.142,95%CI(1.621,5.912)]、不良孕产史[OR=2.989,95%CI(1.218,4.298)]、早孕期体质量增加[OR=1.282,95%CI(1.019,2.296)]、孕前体质量指数(BMI)[OR=1.361,95%CI(1.071,1.721)]、早孕期空腹血糖(FPG)水平[OR=4.042,95%CI(1.591,9.862)]、胰岛素抵抗[OR=1.796,95%CI(1.516,2.619)]等因素和GDM发病密切相关,为其独立危险因素。观察组产妇早产率、剖宫产率高于对照组(P<0.05),其他并发症发生率两组比较差异无统计学意义(P>0.05)。观察组围生儿巨大儿发生率高于对照组(P<0.05),其他并发症发生率两组差异无统计学意义(P>0.05)。结论 GDM发病与多种因素密切相关。在基层医院建立并开展一种GDM筛查、管理的方便可行的科学管理模式,可以有效减少GDM产妇的不良妊娠结局。
目的：探討基層醫院妊娠期糖尿病(GDM)的篩查和管理模式。方法98例GDM產婦為研究對象(觀察組)；選擇同期糖耐量篩查正常的200例產婦為對照組。對GDM產婦實施基層醫院GDM管理模式。統計GDM產婦的一般資料。對GDM相關危險因素進行多因素Logistic迴歸分析。比較觀察組和對照組產婦和圍生兒圍生期併髮癥。結果≥35歲[OR=1.1601,95%CI(1.051,1.310)]、有糖尿病傢族史[OR=3.142,95%CI(1.621,5.912)]、不良孕產史[OR=2.989,95%CI(1.218,4.298)]、早孕期體質量增加[OR=1.282,95%CI(1.019,2.296)]、孕前體質量指數(BMI)[OR=1.361,95%CI(1.071,1.721)]、早孕期空腹血糖(FPG)水平[OR=4.042,95%CI(1.591,9.862)]、胰島素牴抗[OR=1.796,95%CI(1.516,2.619)]等因素和GDM髮病密切相關,為其獨立危險因素。觀察組產婦早產率、剖宮產率高于對照組(P<0.05),其他併髮癥髮生率兩組比較差異無統計學意義(P>0.05)。觀察組圍生兒巨大兒髮生率高于對照組(P<0.05),其他併髮癥髮生率兩組差異無統計學意義(P>0.05)。結論 GDM髮病與多種因素密切相關。在基層醫院建立併開展一種GDM篩查、管理的方便可行的科學管理模式,可以有效減少GDM產婦的不良妊娠結跼。
목적：탐토기층의원임신기당뇨병(GDM)적사사화관리모식。방법98례GDM산부위연구대상(관찰조)；선택동기당내량사사정상적200례산부위대조조。대GDM산부실시기층의원GDM관리모식。통계GDM산부적일반자료。대GDM상관위험인소진행다인소Logistic회귀분석。비교관찰조화대조조산부화위생인위생기병발증。결과≥35세[OR=1.1601,95%CI(1.051,1.310)]、유당뇨병가족사[OR=3.142,95%CI(1.621,5.912)]、불량잉산사[OR=2.989,95%CI(1.218,4.298)]、조잉기체질량증가[OR=1.282,95%CI(1.019,2.296)]、잉전체질량지수(BMI)[OR=1.361,95%CI(1.071,1.721)]、조잉기공복혈당(FPG)수평[OR=4.042,95%CI(1.591,9.862)]、이도소저항[OR=1.796,95%CI(1.516,2.619)]등인소화GDM발병밀절상관,위기독립위험인소。관찰조산부조산솔、부궁산솔고우대조조(P<0.05),기타병발증발생솔량조비교차이무통계학의의(P>0.05)。관찰조위생인거대인발생솔고우대조조(P<0.05),기타병발증발생솔량조차이무통계학의의(P>0.05)。결론 GDM발병여다충인소밀절상관。재기층의원건립병개전일충GDM사사、관리적방편가행적과학관리모식,가이유효감소GDM산부적불량임신결국。
ObjectiveTo investigate the screening and management for gestational diabetes mellitus (GDM) in primary hospital.MethodsThere were 98 puerpera with GDM as study subjects (observation group), and another 200 healthy puerperal as control group. GDM management in primary hospital was applied for GDM puerperal, and their general data were summarized. Related risk factors of GDM were analyzed by multi-factor Logistic regression analysis. Comparison was made on perinatal complications of puerperal and perinatal infants in the two groups.ResultsThe factors of ≥35 years old [OR=1.1601, 95%CI(1.051, 1.310)], family history of diabetes mellitus [OR=3.142, 95%CI(1.621-5.912)], history of abnormal pregnancy [OR=2.989, 95%CI(1.218-4.298)], increased body mass in early gestation [OR=1.282, 95%CI(1.019, 2.296)], progestational body mass index(BMI) [OR=1.361, 95%CI(1.071, 1.721)], fasting plasma glucose(FPG) level in early gestation [OR=4.042, 95%CI(1.591, 9.862)], and insulin resistance [OR=1.796, 95%CI(1.516, 2.619)] were closely related with GDM, and they were independent risk factors of GDM. The observation group had higher premature delivery rate and caesarean section rate than the control group (P<0.05). There was no statistically significant difference of other complications between the two groups (P>0.05). The observation group had higher incidence of fetal macrosomia in perinatal infant than the control group (P<0.05), and the difference of the other complications between the two groups had no statistical significance (P>0.05).ConclusionDue to various related factors of GDM, establishment of a convenient management model for GDM screening and management in primary hospital can effectively reduce adverse pregnancy outcomes of GDM puerperal.
