CAJ | 학술논문

目的：探析中西医结合治疗慢性乙型肝炎肝纤维化及早期肝硬化的效果。方法医院确诊收治的86例慢性活动性乙型肝炎合并肝纤维化及早期肝硬化，符合应用干扰素条件患者，随机分为两组，对照组46例仅采用ɑ-干扰素治疗，观察组40例在对照组治疗基础上增加抗纤汤联合治疗，对患者进行为期6个月的治疗，评价治疗后症状改善、肝纤维化指标检测结果以及肝功能恢复情况。结果治疗后，观察组治疗有效率、基本痊愈率、血清肝纤维化指标水平以及ALT、BIL、A/G、A、γ-G水平与对照组相比，差异有统计学意义，P＜0.05。结论中西医联合用药可有效改善乙肝患者的体征以及临床症状，有利于肝功能的早日恢复，抑制乙肝病毒复制，为治疗慢性乙型肝炎肝纤维化以及早期肝硬化的有效方法。
목적：탐석중서의결합치료만성을형간염간섬유화급조기간경화적효과。방법의원학진수치적86례만성활동성을형간염합병간섬유화급조기간경화，부합응용간우소조건환자，수궤분위량조，대조조46례부채용ɑ-간우소치료，관찰조40례재대조조치료기출상증가항섬탕연합치료，대환자진행위기6개월적치료，평개치료후증상개선、간섬유화지표검측결과이급간공능회복정황。결과치료후，관찰조치료유효솔、기본전유솔、혈청간섬유화지표수평이급ALT、BIL、A/G、A、γ-G수평여대조조상비，차이유통계학의의，P＜0.05。결론중서의연합용약가유효개선을간환자적체정이급림상증상，유리우간공능적조일회복，억제을간병독복제，위치료만성을형간염간섬유화이급조기간경화적유효방법。
Objective To analyze the integrated medicine on the treatment of chronic hepatitis B with liver fibrosis and early cirrhosis of the liver. Methods 86 patients which had chronic active hepatitis B with hepatic fibrosis and early cirrhosis and admitted to the hospital confirmed and accorded with interferon conditions were randomly divided into two groups. The control group of 46 patients used only ɑ-interferon treatment. On the basis of the control group, the observation group of 40 cases used anti -fiber soup for a period of 6 months treatment. The symptom improvement, liver fibrosis test results and recovery of liver function were evaluated. Results After treatment, the treatment efficiency, the basic recovery rate, serum levels of liver fibrosis and ALT, BIL, A / G, A, γ-G levels were combared, the difference was statistically significant ( P<0.05) . Conclusion The integrated medicine can effectively improve the signs and symptoms of hepatitis B patients, and has the advantage of early recovery of liver function, inhibition of HBV replication, and is the effective methods on the treatment of chronic hepatitis B liver fibrosis and early cirrhosis.