CAJ | 학술논문

新辅助化疗已经成为乳腺癌综合治疗的重要组成部分，临床实践中迫切需要一种能准确评价新辅助化疗的方法为临床制订最佳的治疗方案提供依据。近年来，定量磁共振成像技术在早期评价乳腺癌新辅助化疗疗效方面显示出独特的优势。它通过监测肿瘤内一些可量化的参数，可在细胞分子功能水平对经新辅助化疗后肿瘤发生的变化进行客观定量的分析，在肿瘤形态发生改变之前评估乳腺癌新辅助化疗的疗效。因此，定量磁共振成像技术有望成为早期评价乳腺癌新辅助化疗疗效的有效手段。
신보조화료이경성위유선암종합치료적중요조성부분，림상실천중박절수요일충능준학평개신보조화료적방법위림상제정최가적치료방안제공의거。근년래，정량자공진성상기술재조기평개유선암신보조화료료효방면현시출독특적우세。타통과감측종류내일사가양화적삼수，가재세포분자공능수평대경신보조화료후종류발생적변화진행객관정량적분석，재종류형태발생개변지전평고유선암신보조화료적료효。인차，정량자공진성상기술유망성위조기평개유선암신보조화료료효적유효수단。
Neoadjuvant chemotherapy has become an important part of comprehensive therapy for breast cancer.An effective evaluation method to monitor the response to neoadjuvant chemotherapy is urgently required in clinic to provide an important reference for clinicians to choose optimal chemotherapy program . Recently,quantitative magnetic resonance imaging techniques has showed unique advantages in evaluating early response to neoadjuvant chemotherapy in patients with breast cancer.It can objectively and quantitatively ana-lyze the changes in tumor at the level of cellular and molecular after neoadjuvant chemotherapy by monitoring quantifiable parameters in tumor so as to early predict the response to neoadjuvant chemotherapy before the tumor morphology changes.Therefore, quantitative magnetic resonance imaging techniques is expected to become an effective means in evaluating the response of breast cancer to neoadjuvant chemotherapy .