医学综述
醫學綜述
의학종술
MEDICAL RECAPITULATE
2015年
8期
1425-1426,1429
,共3页
何帆%毛静瑞(综述)%蔡在龙(审校)
何帆%毛靜瑞(綜述)%蔡在龍(審校)
하범%모정서(종술)%채재룡(심교)
多囊卵巢综合征%基因%胰岛素%肥胖
多囊卵巢綜閤徵%基因%胰島素%肥胖
다낭란소종합정%기인%이도소%비반
Polycystic ovary syndrome%Gene%Insulin%Obesity
多囊卵巢综合征（ PCOS）是生育期女性最常见的内分泌失调疾病，育龄妇女中发病率为5％～10％，现今其发病率有所上升。 PCOS的病因众多，普遍认为PCOS是由多个微效基因与环境因素相互作用而引起的一种多基因遗传性疾病；此外，肥胖、高胰岛素血症者患PCOS的概率也会增加，而精神心理因素对PCOS的发病也有一定的影响。其发病机制复杂，最重要的是与雄激素分泌过量、胰岛素抵抗密切相关。
多囊卵巢綜閤徵（ PCOS）是生育期女性最常見的內分泌失調疾病，育齡婦女中髮病率為5％～10％，現今其髮病率有所上升。 PCOS的病因衆多，普遍認為PCOS是由多箇微效基因與環境因素相互作用而引起的一種多基因遺傳性疾病；此外，肥胖、高胰島素血癥者患PCOS的概率也會增加，而精神心理因素對PCOS的髮病也有一定的影響。其髮病機製複雜，最重要的是與雄激素分泌過量、胰島素牴抗密切相關。
다낭란소종합정（ PCOS）시생육기녀성최상견적내분비실조질병，육령부녀중발병솔위5％～10％，현금기발병솔유소상승。 PCOS적병인음다，보편인위PCOS시유다개미효기인여배경인소상호작용이인기적일충다기인유전성질병；차외，비반、고이도소혈증자환PCOS적개솔야회증가，이정신심리인소대PCOS적발병야유일정적영향。기발병궤제복잡，최중요적시여웅격소분비과량、이도소저항밀절상관。
Polycystic ovary syndrome(PCOS) is one of the most common endocrine disorders affecting women of reproductive age with an incidence of 5%-10%of them,which has been rising.PCOS has a diverse range of causes.It is widely believed that PCOS is a polygenic hereditary disease caused by the interaction of multiple minor genes and environment factors;besides,obesity and hyperinsulinemia may increase the risk of PCOS,while psychological factors have a certain influence on PCOS as well .The pathogenesis of PCOS is complicated and closely related to excessive androgen secretion and insulin resistance in particular .
