医学综述
醫學綜述
의학종술
MEDICAL RECAPITULATE
2015年
8期
1385-1387
,共3页
李婷(综述)%李晓波(审校)
李婷(綜述)%李曉波(審校)
리정(종술)%리효파(심교)
颅内动脉瘤%蛛网膜下腔出血%易患基因%单核苷酸多态性
顱內動脈瘤%蛛網膜下腔齣血%易患基因%單覈苷痠多態性
로내동맥류%주망막하강출혈%역환기인%단핵감산다태성
Intracranial aneurysms%Subarachnoid hemorrhage%Susceptibility gene%Single nucleotide polymorphism
颅内动脉瘤（ IAs）是颅内动脉壁的异常膨出，在脑血管意外引起蛛网膜下腔出血（ SAH）疾病中排第三位，仅次于脑血管栓塞和高血压性脑出血。该病起病急、病程短，对身体危害大。目前研究证实，IAs成因与环境因素和遗传因素有关，并且遗传因素在IAs形成中的作用已得到共识。该文从近年IAs相关基因研究着手，对IAs与相关易患基因研究进展予以综述。
顱內動脈瘤（ IAs）是顱內動脈壁的異常膨齣，在腦血管意外引起蛛網膜下腔齣血（ SAH）疾病中排第三位，僅次于腦血管栓塞和高血壓性腦齣血。該病起病急、病程短，對身體危害大。目前研究證實，IAs成因與環境因素和遺傳因素有關，併且遺傳因素在IAs形成中的作用已得到共識。該文從近年IAs相關基因研究著手，對IAs與相關易患基因研究進展予以綜述。
로내동맥류（ IAs）시로내동맥벽적이상팽출，재뇌혈관의외인기주망막하강출혈（ SAH）질병중배제삼위，부차우뇌혈관전새화고혈압성뇌출혈。해병기병급、병정단，대신체위해대。목전연구증실，IAs성인여배경인소화유전인소유관，병차유전인소재IAs형성중적작용이득도공식。해문종근년IAs상관기인연구착수，대IAs여상관역환기인연구진전여이종술。
Intracranial aneurysm(IA) is the abnormal bulging in brain artery walls,it ranks the third among the cerebral vascular accidents causing subarachnoid hemorrhage ( SAH ) , second only to cerebral embolism and hypertensive intracerebral hemorrhage.IA is characterized by rapid onset,short duration,and great harm to the body.Current studies have confirmed the causes for IA is correlated with environmental fac-tors and genetic factors,and the role of genetic factors in IA formation has come to a consensus .Here is to make a review of the research progress on relevant IA susceptibility genes basing on studies in recent years .
