CAJ | 학술논문

代谢综合征(metabolic syndrome,MS)是一种多基因遗传的复杂疾病,由多个基因累加作用和某些环境因素影响所致。胰岛素抵抗是其病理生理基础。从中医学角度看,痰是MS共同的证候病理特点,痰的病理贯穿MS全过程。基因作为先天因素的重要组成部分,在痰证的形成中发挥重要作用。研究MS痰证与易感基因的相关性,对于进一步丰富痰证的内涵、提高本病诊疗水平具有十分重要的意义。
대사종합정(metabolic syndrome,MS)시일충다기인유전적복잡질병,유다개기인루가작용화모사배경인소영향소치。이도소저항시기병리생리기출。종중의학각도간,담시MS공동적증후병리특점,담적병리관천MS전과정。기인작위선천인소적중요조성부분,재담증적형성중발휘중요작용。연구MS담증여역감기인적상관성,대우진일보봉부담증적내함、제고본병진료수평구유십분중요적의의。
Metabolic syndrome (MS) is a complex polygenic inheritance disease, caused by the accumulative effect of multiple genes and some environmental factors. Insulin resistance is the pathophysiologic foundation of MS. From the viewpoint of TCM, phlegm is the basic pathological factor of MS. In different periods and different symptoms of the disease, phlegm can be found during the whole disease course. Genes as an important component of the innate factors, play an important role in the formation of phlegm syndrome. Researches on correlation between susceptibility genes and phlegm syndrome in MS are important to enrich the connotation of phlegm syndrome and improve the level of diagnosis and treatment for this disease.