CAJ | 학술논문

【目的】探讨骨密度测定在中老年心脑血管疾病患者中的临床意义，进一步了解骨质疏松与心血管疾病的关系。【方法】对本院347例中老年心脑血管病患者行骨密度检测，并按检测结果分为三组（骨量正常组，骨量减少组，骨质疏松组），记录收缩压（SBP）、舒张压（DBP）、总胆固醇（TC）、三酯甘油（TG）、低密度脂蛋白胆固醇（LDL‐C ）、高密度脂蛋白胆固醇（HDL‐C ）等指标。【结果】高血压病、冠心病、脑血管病各疾病中骨质疏松，骨量减少者发生率明显高于骨量正常者，且差异均有显著性（χ2值分别为8．46，5．02，4．37，均 P＜0．05）。各组女性骨质疏松发生率发生率高于男性，且差异均有显著性（χ2值分别为14．62，8．97，6．44，均 P＜0．05）。骨质疏松组血压、TC、HDL‐C较骨量正常组明显升高，且差异有显著性（ P ＜0．05或 P ＜0．01）。【结论】骨密度是中老年心脑血管疾病患者需要监测的指标，骨质疏松与心脑血管疾病危险因素有内在关系，其有着相同的病理生理机制。
【목적】탐토골밀도측정재중노년심뇌혈관질병환자중적림상의의，진일보료해골질소송여심혈관질병적관계。【방법】대본원347례중노년심뇌혈관병환자행골밀도검측，병안검측결과분위삼조（골량정상조，골량감소조，골질소송조），기록수축압（SBP）、서장압（DBP）、총담고순（TC）、삼지감유（TG）、저밀도지단백담고순（LDL‐C ）、고밀도지단백담고순（HDL‐C ）등지표。【결과】고혈압병、관심병、뇌혈관병각질병중골질소송，골량감소자발생솔명현고우골량정상자，차차이균유현저성（χ2치분별위8．46，5．02，4．37，균 P＜0．05）。각조녀성골질소송발생솔발생솔고우남성，차차이균유현저성（χ2치분별위14．62，8．97，6．44，균 P＜0．05）。골질소송조혈압、TC、HDL‐C교골량정상조명현승고，차차이유현저성（ P ＜0．05혹 P ＜0．01）。【결론】골밀도시중노년심뇌혈관질병환자수요감측적지표，골질소송여심뇌혈관질병위험인소유내재관계，기유착상동적병리생리궤제。
[Objective] To explore the clinical significance of bone mineral density (BMD ) detection in middle‐aged and elderly patients with cardiocerebrovascular diseases for further elucidating the relationship be‐tween osteoporosis and cardiocerebrovascular diseases .[Methods] BMD was measured by dual‐energy X‐ray absorptiometry .A total of 347 patients with cardiocerebrovascular diseases were divided into three groups of normal BMD ,low BMD and osteoporosis .And analyses were performed for the parameters of systolic blood pressure (SBP) ,diastolic blood pressure (DBP) ,total cholesterol (TC) ,serum triglyceride (TG) ,low densi‐ty lipoprotein (LDL‐C) and high density lipoprotein (HDL‐C) .[Results] The value of BMD was low among kinds of cardiocerebrovascular diseases ,the morbidity of osteoporosis was high .Significant differences existed in blood pressure , TC and HDL‐C among three BMD groups ( P < 0 .01 ) .[Conclusion] BMD detection should be monitored for cardiocerebrovascular diseases .Close correlations exist between osteoporosis and car‐diovascular risk factors .And there are some common pathophysiologic mechanisms .