中国中医药信息杂志
中國中醫藥信息雜誌
중국중의약신식잡지
CHINESE JOURNAL OF INFORMATION ON TRADITIONAL CHINESE MEDICINE
2015年
6期
35-38
,共4页
多囊卵巢综合征%益肾助阳活血化浊方加味%卵巢多囊样改变
多囊卵巢綜閤徵%益腎助暘活血化濁方加味%卵巢多囊樣改變
다낭란소종합정%익신조양활혈화탁방가미%란소다낭양개변
polycystic ovarian syndrome%modified Yishen Zhuyang Huoxue Huazhuo Formula%changes of polycystic ovary
目的：观察益肾助阳活血化浊方加味对多囊卵巢综合征(PCOS)脾肾两虚痰湿证患者卵巢病理状态的影响及其安全性。方法将123例患者采用计算机中央随机法分为观察组64例和对照组59例,观察组口服益肾助阳活血化浊方加味,对照组口服复方醋酸环丙孕酮片,2组均以3个月为1个疗程,连续治疗2个疗程。观察2组患者治疗前后卵巢体积及卵泡数目变化,并评价其安全性。结果观察组和对照组患者双侧卵巢体积均较治疗前缩小(P＜0.05,P＜0.01),对照组疗效更明显(P＜0.01)。2组治疗后卵泡数目均有减少趋势,组间比较差异无统计学意义(P＞0.05)。观察组不良反应率低于对照组。结论益肾助阳活血化浊方加味治疗 PCOS能使异常增大的卵巢体积缩小或复常,且不良反应少。
目的：觀察益腎助暘活血化濁方加味對多囊卵巢綜閤徵(PCOS)脾腎兩虛痰濕證患者卵巢病理狀態的影響及其安全性。方法將123例患者採用計算機中央隨機法分為觀察組64例和對照組59例,觀察組口服益腎助暘活血化濁方加味,對照組口服複方醋痠環丙孕酮片,2組均以3箇月為1箇療程,連續治療2箇療程。觀察2組患者治療前後卵巢體積及卵泡數目變化,併評價其安全性。結果觀察組和對照組患者雙側卵巢體積均較治療前縮小(P＜0.05,P＜0.01),對照組療效更明顯(P＜0.01)。2組治療後卵泡數目均有減少趨勢,組間比較差異無統計學意義(P＞0.05)。觀察組不良反應率低于對照組。結論益腎助暘活血化濁方加味治療 PCOS能使異常增大的卵巢體積縮小或複常,且不良反應少。
목적：관찰익신조양활혈화탁방가미대다낭란소종합정(PCOS)비신량허담습증환자란소병리상태적영향급기안전성。방법장123례환자채용계산궤중앙수궤법분위관찰조64례화대조조59례,관찰조구복익신조양활혈화탁방가미,대조조구복복방작산배병잉동편,2조균이3개월위1개료정,련속치료2개료정。관찰2조환자치료전후란소체적급란포수목변화,병평개기안전성。결과관찰조화대조조환자쌍측란소체적균교치료전축소(P＜0.05,P＜0.01),대조조료효경명현(P＜0.01)。2조치료후란포수목균유감소추세,조간비교차이무통계학의의(P＞0.05)。관찰조불량반응솔저우대조조。결론익신조양활혈화탁방가미치료 PCOS능사이상증대적란소체적축소혹복상,차불량반응소。
Objective To observe the effect and safety of modified Yishen Zhuyang Huoxue Huazhuo Formula for polycystic ovarian syndrome (PCOS) in the TCM pattern of deficiency of spleen and kidney with phlegm-dampness. Methods Totally 123 cases were recruited into this study and randomized to two groups by central random approach, 64 cases in the observation group and 59 cases in the control group. Patients in the observation group were given the modified Yishen Zhuyang Huoxue Huazhuo Formula, while those in the control group were given compound cyproterone acetate tablet, for two treatment courses, three months for one course. The changes of ovarian volume and the number of follicles before and after treatment were observed. Adverse reactions were also evaluated. Results Bilateral ovarian volumes in both groups decreased after treatment (P<0.05, P<0.01), while the control group showed a significant better improvement (P<0.05). The number of follicles in the two groups decreased, but no significant difference were observed between the two groups (P>0.05). The rate of adverse reaction in the observation group was lower than the control group. Conclusion Modified Yishen Zhuyang Huoxue Huazhuo Formula is effective for PCOS patient by reducing the ovarian volume with a low incidence of side effect.
