CAJ | 학술논문

目的：探讨人乳头瘤病毒(HPV)DNA检测和宫颈细胞学检查对宫颈癌前病变筛查的效果。方法选取2013年1月~2014年6月来本院就诊并进行宫颈癌前病变筛查的1100例患者，均进行HPV DNA检测、宫颈细胞学检查、阴道镜检查与宫颈活检，以病理诊断为标准，对检测结果进行分析。结果1100例患者中，HPV DNA阳性率为23.00豫，其中宫颈癌阳性率为83.33豫，宫颈上皮内瘤变(CIN)Ⅰ阳性率为44.44豫，CINⅡ阳性率为86.67豫，CINⅢ阳性率为94.12豫。宫颈细胞学检查无CIN 851例(77.36豫)，非典型鳞状上皮细胞139例(12.64豫)，低度鳞状上皮细胞内病变78例(7.09豫)，高度鳞状上皮细胞内病变29例(2.64豫)，鳞状细胞癌3例(0.27豫)。阴道镜检查与病理诊断符合率为62.79豫(54/86)。结论针对就诊患者采取合适的宫颈癌前病变筛查方法有助于提高检出率，降低宫颈癌发生率。
목적：탐토인유두류병독(HPV)DNA검측화궁경세포학검사대궁경암전병변사사적효과。방법선취2013년1월~2014년6월래본원취진병진행궁경암전병변사사적1100례환자，균진행HPV DNA검측、궁경세포학검사、음도경검사여궁경활검，이병리진단위표준，대검측결과진행분석。결과1100례환자중，HPV DNA양성솔위23.00예，기중궁경암양성솔위83.33예，궁경상피내류변(CIN)Ⅰ양성솔위44.44예，CINⅡ양성솔위86.67예，CINⅢ양성솔위94.12예。궁경세포학검사무CIN 851례(77.36예)，비전형린상상피세포139례(12.64예)，저도린상상피세포내병변78례(7.09예)，고도린상상피세포내병변29례(2.64예)，린상세포암3례(0.27예)。음도경검사여병리진단부합솔위62.79예(54/86)。결론침대취진환자채취합괄적궁경암전병변사사방법유조우제고검출솔，강저궁경암발생솔。
Objective To investigate the effect of human papillomavirus (HPV) DNA testing and cervical cytology screening of cervical precancerous lesions. Methods 1100 patients admitted to our hospital who were carried out screening cervical precancerous lesions from January 2013 to June 2014 were selected,all were carried out HPV DNA testing,cervical cytology,colposcopy and cervical biopsy,pathological diagnosis was as the standard,the test results were analyzed. Results Positive rate of HPV DNA testing was 23.00% in 1100 patients,in which,positive rate of cervical cancer was 83.33%,positive rate of cervical intraepithelial neoplasia (CIN) Ⅰ was 44.44%,CIN II testing was 86.67%, CINⅢ positive rate was 94.12%.Cervical cytology results showed that there were 851 cases (77.36%) with no CIN,139 cases (12.64%) were atypical squamous cells,78 cases (7.09%) were low-grade squamous intraepithelial lesion,29 cases (2.64%) of high-grade squamous intraepithelial cells lesions,3 cases (0.27%) of squamous cell carcinoma.The compli-ance rate of colposcopy examination and pathological diagnosis was 62.79% (54/86). Conclusion The suitable cervical lesions screening method for patients can help to improve the detection rate,reduce the incidence rate of cervical cancer.