中国当代医药
中國噹代醫藥
중국당대의약
PERSON
2015年
13期
45-47
,共3页
双水平正压通气%小儿重症毛细支气管炎%临床疗效
雙水平正壓通氣%小兒重癥毛細支氣管炎%臨床療效
쌍수평정압통기%소인중증모세지기관염%림상료효
Bi-level positive airway pressure (BiPAP)%Children with severe capillary bronchitis%Clinical efficacy
目的：探讨采用双水平正压通气治疗小儿重症毛细支气管炎的临床疗效。方法选取2011年12月~2014年10月本院收治的97例重症小儿毛细支气管炎患儿，分为治疗组(48例)和常规组(49例)，常规组给予抗感染、平喘、雾化吸痰、糖皮质激素等治疗，治疗组在常规组治疗基础上采用双水平正压通气进行辅助治疗，比较两组患儿的临床症状缓解时间、治疗3d后的临床效果及动脉血气分析变化差异。结果治疗组患儿心率好转时间、呼吸困难消失时间、肺部湿啰音消失时间均显著短于常规组，差异有统计学意义(P<0.05)。治疗3 d后，治疗组患儿的HR(112.9±13.6/min)、pH值(7.32±0.09)、PaO2[(85.6±9.4) mm Hg]、PaCO2[(48.4±6.4) mm Hg]、PaO2/FiO2[(221.3±16.5)mm Hg]均显著优于常规组，差异有统计学意义(P<0.05)；治疗组临床疗效分布显著优于常规组，差异有统计学意义(P<0.05)；治疗组的总有效率(93.75%)显著高于常规组(77.08%)，差异有统计学意义(P<0.05)。结论双水平正压通气治疗能改善小儿重症毛细支气管炎的临床症状，纠正血气指标，提高临床疗效。
目的：探討採用雙水平正壓通氣治療小兒重癥毛細支氣管炎的臨床療效。方法選取2011年12月~2014年10月本院收治的97例重癥小兒毛細支氣管炎患兒，分為治療組(48例)和常規組(49例)，常規組給予抗感染、平喘、霧化吸痰、糖皮質激素等治療，治療組在常規組治療基礎上採用雙水平正壓通氣進行輔助治療，比較兩組患兒的臨床癥狀緩解時間、治療3d後的臨床效果及動脈血氣分析變化差異。結果治療組患兒心率好轉時間、呼吸睏難消失時間、肺部濕啰音消失時間均顯著短于常規組，差異有統計學意義(P<0.05)。治療3 d後，治療組患兒的HR(112.9±13.6/min)、pH值(7.32±0.09)、PaO2[(85.6±9.4) mm Hg]、PaCO2[(48.4±6.4) mm Hg]、PaO2/FiO2[(221.3±16.5)mm Hg]均顯著優于常規組，差異有統計學意義(P<0.05)；治療組臨床療效分佈顯著優于常規組，差異有統計學意義(P<0.05)；治療組的總有效率(93.75%)顯著高于常規組(77.08%)，差異有統計學意義(P<0.05)。結論雙水平正壓通氣治療能改善小兒重癥毛細支氣管炎的臨床癥狀，糾正血氣指標，提高臨床療效。
목적：탐토채용쌍수평정압통기치료소인중증모세지기관염적림상료효。방법선취2011년12월~2014년10월본원수치적97례중증소인모세지기관염환인，분위치료조(48례)화상규조(49례)，상규조급여항감염、평천、무화흡담、당피질격소등치료，치료조재상규조치료기출상채용쌍수평정압통기진행보조치료，비교량조환인적림상증상완해시간、치료3d후적림상효과급동맥혈기분석변화차이。결과치료조환인심솔호전시간、호흡곤난소실시간、폐부습라음소실시간균현저단우상규조，차이유통계학의의(P<0.05)。치료3 d후，치료조환인적HR(112.9±13.6/min)、pH치(7.32±0.09)、PaO2[(85.6±9.4) mm Hg]、PaCO2[(48.4±6.4) mm Hg]、PaO2/FiO2[(221.3±16.5)mm Hg]균현저우우상규조，차이유통계학의의(P<0.05)；치료조림상료효분포현저우우상규조，차이유통계학의의(P<0.05)；치료조적총유효솔(93.75%)현저고우상규조(77.08%)，차이유통계학의의(P<0.05)。결론쌍수평정압통기치료능개선소인중증모세지기관염적림상증상，규정혈기지표，제고림상료효。
Objective To explore the clinical efficacy of bi-level positive airway pressure (BiPAP) on treating children with severe capillary bronchitis. Methods 97 children with severe capillary bronchitis in our hospital from December 2011 to October 2014 were selected and divided into treatment group(n=48) and conventional group(n=49).Therapies of anti-infection,panting alleviation,atomization suctioning and glucocorticoid were adopted in conventional group;while on the basis of conventional group,BiPAP as an adjuvant therapy was applied in treatment group.The alleviation time of clinical symptoms,clinical efficacy after 3 d treatment,and difference of arterial blood gas between two groups were compared. Results Time of heart rate improving,disappearing of dyspnea,disappearing of pulmonary moist rales in treat-ment group were greatly shorter than that in conventional group,with statistical differences (P<0.05).In treatment group, HR (112.9±13.6/min),pH value (7.32±0.09),PaO2 [(85.6±9.4) mm Hg],PaCO2 [(48.4±6.4) mm Hg],and PaO2/FiO2 [(221.3±16.5) mm Hg] which were all superior to that in conventional group,with statistical differences(P<0.05).Clinical efficacy after 3 d treatment in treatment group was superior to that in conventional group,with statistical difference (P<0.05).The total effective rate in treatment group was 93.75%,higher than that in conventional group accounting for 77.08%,with a statistical difference (P<0.05). Conclusion BiPAP can improve clinical symptoms and signs of severe capillary bronchi-tis in children and rectify blood gas index in order to improve clinical efficacy.
