CAJ | 학술논문

目的：探究中西医联合治疗对慢性心力衰竭的临床疗效。方法选取2013年1月—2013年12月我院80例慢性心力衰竭患者为研究对象,并将研究对象以数字法随机分为观察组和对照组,各40例。对照组行常规西药治疗,口服螺内酯、卡托普利片；观察组在对照组西医基础治疗上加用参附注射液。分析两组治疗效果,观察治疗前后中医证候积分及心功能分级；检测治疗前后三碘甲状腺原氨酸(T3)、甲状腺素(T4)的含量。结果观察组治疗后总有效率为77.50%,高于对照组为35.00%；观察组治疗后中医证候积分为轻度18例,对照组9例；观察组患者治疗后三碘甲状腺原氨酸含量为(0.85±0.28)ng/mL,比对照组的(0.69±0.27)ng/mL更接近正常值。而 T4值治疗前后无显著变化。3组数据比较差异均有统计学意义(P<0.05)。结论慢性心力衰竭具有难根治、死亡率高等特点,在保证治疗效率的前提下选择中西药联合法延缓和预防心肌重构的发展效果较好。建议为治疗慢性心力衰竭的推荐方案。
목적：탐구중서의연합치료대만성심력쇠갈적림상료효。방법선취2013년1월—2013년12월아원80례만성심력쇠갈환자위연구대상,병장연구대상이수자법수궤분위관찰조화대조조,각40례。대조조행상규서약치료,구복라내지、잡탁보리편；관찰조재대조조서의기출치료상가용삼부주사액。분석량조치료효과,관찰치료전후중의증후적분급심공능분급；검측치료전후삼전갑상선원안산(T3)、갑상선소(T4)적함량。결과관찰조치료후총유효솔위77.50%,고우대조조위35.00%；관찰조치료후중의증후적분위경도18례,대조조9례；관찰조환자치료후삼전갑상선원안산함량위(0.85±0.28)ng/mL,비대조조적(0.69±0.27)ng/mL경접근정상치。이 T4치치료전후무현저변화。3조수거비교차이균유통계학의의(P<0.05)。결론만성심력쇠갈구유난근치、사망솔고등특점,재보증치료효솔적전제하선택중서약연합법연완화예방심기중구적발전효과교호。건의위치료만성심력쇠갈적추천방안。
Objective To explore the effect of integrative Chinese and western medicine for treatment chronic heart failure.Methods Eighty patients with chronic heart failure randomly divided into two groups:The control group(n=40)treated with routine western medicine treatment,the observation group (n =40)treated with routine western medicine treatment plus Shenfu injection.The effects,Chinese medicine symptom integral and cardiac function classification were observed.The content of T3 and T4 were detec-ted.Results The total effective rate was 77.50% in observation group,which was higher than that in control group(35.00%,P<0.05). After treatment,TCM symptom integral mild was 18 cases in observation group and 9 cases in control group.The content of T3 was 0.85± 0.28 in observation group and 0.69± 0.27 in control group.Conclusion The integrative Chinese and western medicine for treatment chronic heart failure had an obvious effect.