CAJ | 학술논문

目的：探讨 ST段抬高型心肌梗死(SETMI)患者不同时间经桡动脉行冠状动脉介入术(PCI)的安全性和有效性。方法选取 ST段抬高型心肌梗死患者连续病例100例并分为两类,即就诊时间12 h内直接进行 PCI的连续病例35例(A组)、溶栓后12 h内进行 PCI的连续病例65例(B组)。主要测定终点是 PCI术后患者的心肌灌注水平,将患者在治疗期间的出血并发症发生率和规定时间内的心脏不良事件(MACE)发生情况作为次要终点事件。结果 A组的 IRA血栓积分偏低,而通过 TIMI血流分级(TFG)和 TIMI记帧(CTFC)测量的血流级别显示3级的比例高些(P<0.05)。A组和 B组的 CTFC数值有着很大的差别,A组大于 B组[(27.32±4.95)vs(31.04±9.03),P<0.05],而 TMPC的3级比例 B组高于 A组。肌酸激酶同工酶(CK MB)峰值 B组有下降趋势。出血并发症发生率、MACE发生率对于测定结果没有直接的影响。结论溶栓后早期经桡动脉行 PCI治疗安全有效,值得临床重视。
목적：탐토 ST단태고형심기경사(SETMI)환자불동시간경뇨동맥행관상동맥개입술(PCI)적안전성화유효성。방법선취 ST단태고형심기경사환자련속병례100례병분위량류,즉취진시간12 h내직접진행 PCI적련속병례35례(A조)、용전후12 h내진행 PCI적련속병례65례(B조)。주요측정종점시 PCI술후환자적심기관주수평,장환자재치료기간적출혈병발증발생솔화규정시간내적심장불량사건(MACE)발생정황작위차요종점사건。결과 A조적 IRA혈전적분편저,이통과 TIMI혈류분급(TFG)화 TIMI기정(CTFC)측량적혈류급별현시3급적비례고사(P<0.05)。A조화 B조적 CTFC수치유착흔대적차별,A조대우 B조[(27.32±4.95)vs(31.04±9.03),P<0.05],이 TMPC적3급비례 B조고우 A조。기산격매동공매(CK MB)봉치 B조유하강추세。출혈병발증발생솔、MACE발생솔대우측정결과몰유직접적영향。결론용전후조기경뇨동맥행 PCI치료안전유효,치득림상중시。
Objective To investigate the safety and effectiveness of different time transradial percutaneous coronary intervention (PCI)in patients with ST segment elevation myocardial infarction(SETMI).Methods One hundred patients with SETMI were divided into two groups:Group A(n=35)undergoing directly consecutive PCI within 12 h,and group B (n=65)undergoing PCI after thrombolysis within 12 h.The main endpoint was the determination of the level of myocardial perfusion in patients after PCI staff wil major adverse cardiac events (MACE)incidence of bleeding complications in patients with officers during the time of treatment and the occurrence of specified as a secondary endpoint.Results The results could be seen from the results of group A low credit infarct related artery (IRA)thrombus,and blood levels by thrombolysis in myocardial infarction (TIMI)flow grade (TFG)and corrected TIMI frame count(CTFC)levels measured 3 ratio higher (P<0.05).The CTFC values in group A were more than that in group B[(27.32± 4.95)vs (31.04± 9.03),P<0.05].The proportion of TMPG's three in group B was higher than that in group A.From CK MB peak point of view in group B,there was a downward trend.The incidence of bleeding complications,MACE rates had no direct effect on the measurement results.Conclusion Early transradial PCI after thrombolysis is safe and effective.