中国医药科学
中國醫藥科學
중국의약과학
CHINA MEDICINE AND PHARMACY
2015年
7期
211-213
,共3页
孕前筛查%地中海贫血%优生优育%基因
孕前篩查%地中海貧血%優生優育%基因
잉전사사%지중해빈혈%우생우육%기인
Progestational screening%Thalassanemia%Prepotency%Gene
目的：了解佛山市三水区孕前优生健康检查对象地中海贫血发病情况，为制定降低出生缺陷发生率干预措施提供理论依据。方法对自2013年9月~2014年9月三水区7842对孕前优生夫妇进行地中海贫血筛查，初筛指标包括平均红细胞体积（MCV）、平均红细胞血红蛋白含量（MCH），初筛异常者进行地中海贫血基因检查。结果地中海贫血初筛阳性1563人，占9.96%；夫妇双方地贫筛查阳性进一步地贫基因检查66对，筛查阳性夫妇基因检查确诊率为84.85%。结论广东是地中海贫血的高发地区，孕前对地中海贫血进行筛查可以降低地中海贫血新生儿的发生率，对降低出生缺陷、避免中重度地中海贫血患儿出生、提高人口质量有极其重要的现实意义，应该加大宣传力度，提高人群的健康筛查意识，为优生优育计划提供强劲的支撑。
目的：瞭解彿山市三水區孕前優生健康檢查對象地中海貧血髮病情況，為製定降低齣生缺陷髮生率榦預措施提供理論依據。方法對自2013年9月~2014年9月三水區7842對孕前優生伕婦進行地中海貧血篩查，初篩指標包括平均紅細胞體積（MCV）、平均紅細胞血紅蛋白含量（MCH），初篩異常者進行地中海貧血基因檢查。結果地中海貧血初篩暘性1563人，佔9.96%；伕婦雙方地貧篩查暘性進一步地貧基因檢查66對，篩查暘性伕婦基因檢查確診率為84.85%。結論廣東是地中海貧血的高髮地區，孕前對地中海貧血進行篩查可以降低地中海貧血新生兒的髮生率，對降低齣生缺陷、避免中重度地中海貧血患兒齣生、提高人口質量有極其重要的現實意義，應該加大宣傳力度，提高人群的健康篩查意識，為優生優育計劃提供彊勁的支撐。
목적：료해불산시삼수구잉전우생건강검사대상지중해빈혈발병정황，위제정강저출생결함발생솔간예조시제공이론의거。방법대자2013년9월~2014년9월삼수구7842대잉전우생부부진행지중해빈혈사사，초사지표포괄평균홍세포체적（MCV）、평균홍세포혈홍단백함량（MCH），초사이상자진행지중해빈혈기인검사。결과지중해빈혈초사양성1563인，점9.96%；부부쌍방지빈사사양성진일보지빈기인검사66대，사사양성부부기인검사학진솔위84.85%。결론엄동시지중해빈혈적고발지구，잉전대지중해빈혈진행사사가이강저지중해빈혈신생인적발생솔，대강저출생결함、피면중중도지중해빈혈환인출생、제고인구질량유겁기중요적현실의의，응해가대선전력도，제고인군적건강사사의식，위우생우육계화제공강경적지탱。
Objective To understand the thalassanemia incidence of progestational aristogenesis in health examination objects of Sanshui District in Foshan City, in order to provide the theoretical basis to formulate intervention measures to reduce the incidence of birth defects. Methods 7842 couples with progestational aristogenesis were screened on thalassanemia in Sanshui District from September 2013 to September 2014, with the indexes of preliminary screening of mean corpuscular volume (MCV) and mean corpuscular hemoglobin (MCH), while abnormal patients of preliminary screening were made with gene examination of thalassanemia.ResultsThe positive of preliminary screening of thalassanemia was 1563 patients(9.96%), 66 couples with positive of preliminary screening were made with gene examination of thalassanemia, while the diagnosis rate of gene examination in couples with positive of preliminary screening was 84.85%.ConclusionGuangdong is high prevalence area of thalassanemia. Progestational screening of thalassanemia could reduce the incidence of thalassanemia in newborns, has extremely important practical significance to reduce birth defects, to avoid the birth of children with moderate or severe thalassanemia, and to improve the population quality, should be vigorously propagandized to improve people's consciousness of health screening and to provide forceful support for prepotent plan.
