中国医药科学
中國醫藥科學
중국의약과학
CHINA MEDICINE AND PHARMACY
2015年
7期
157-158,165
,共3页
芬必得%尼美舒利%疼痛%联合应用
芬必得%尼美舒利%疼痛%聯閤應用
분필득%니미서리%동통%연합응용
Fenbid%Nimesulide%Pain%Combined application
目的：探讨短期联合使用芬必得和尼美舒利治疗以疼痛就诊的临床效果。方法以我院96例以疼痛就诊患者为研究对象，A组患者单独使用芬必得治疗，B组患者单独使用尼美舒利治疗，C组患者联合使用芬必得、尼美舒利治疗，对三组的短期治疗效果进行比较分析。结果 A组用药3d后疼痛缓解总有效率为53.13%，B组用药三天后总有效率为65.63%，C组用药3d后总有效率为90.63%，用药3d后C组疼痛缓解效果明显好于A组、B组（P＜0.05），A组和B组改善效果差异无统计学意义（P＞0.05）；用药1周后A组、B组和C组患者的不良反应发生率3.13%、0和3.13%，A组1例胃部不适，B组0例，C组1例胃部不适。无其他不良反应，组间比较差异无统计学意义（P＞0.05）。三组用药后各项凝血指标均无异常。结论芬必得与尼美舒利联合治疗疼痛短期效果明显，未发现无明显不良反应，联合应用可以应用于短期治疗。
目的：探討短期聯閤使用芬必得和尼美舒利治療以疼痛就診的臨床效果。方法以我院96例以疼痛就診患者為研究對象，A組患者單獨使用芬必得治療，B組患者單獨使用尼美舒利治療，C組患者聯閤使用芬必得、尼美舒利治療，對三組的短期治療效果進行比較分析。結果 A組用藥3d後疼痛緩解總有效率為53.13%，B組用藥三天後總有效率為65.63%，C組用藥3d後總有效率為90.63%，用藥3d後C組疼痛緩解效果明顯好于A組、B組（P＜0.05），A組和B組改善效果差異無統計學意義（P＞0.05）；用藥1週後A組、B組和C組患者的不良反應髮生率3.13%、0和3.13%，A組1例胃部不適，B組0例，C組1例胃部不適。無其他不良反應，組間比較差異無統計學意義（P＞0.05）。三組用藥後各項凝血指標均無異常。結論芬必得與尼美舒利聯閤治療疼痛短期效果明顯，未髮現無明顯不良反應，聯閤應用可以應用于短期治療。
목적：탐토단기연합사용분필득화니미서리치료이동통취진적림상효과。방법이아원96례이동통취진환자위연구대상，A조환자단독사용분필득치료，B조환자단독사용니미서리치료，C조환자연합사용분필득、니미서리치료，대삼조적단기치료효과진행비교분석。결과 A조용약3d후동통완해총유효솔위53.13%，B조용약삼천후총유효솔위65.63%，C조용약3d후총유효솔위90.63%，용약3d후C조동통완해효과명현호우A조、B조（P＜0.05），A조화B조개선효과차이무통계학의의（P＞0.05）；용약1주후A조、B조화C조환자적불량반응발생솔3.13%、0화3.13%，A조1례위부불괄，B조0례，C조1례위부불괄。무기타불량반응，조간비교차이무통계학의의（P＞0.05）。삼조용약후각항응혈지표균무이상。결론분필득여니미서리연합치료동통단기효과명현，미발현무명현불량반응，연합응용가이응용우단기치료。
Objective To explore the clinical effects of fenbid short-term combined with nimesulide in the treatment of patients with pain. Methods96 patients with pain in our hospital were selected as research objects. Patients in group A were treated with Fenbid only.Patients in group B were treated with nimesulide only.Patients in group C were treated with combination of fenbid and nimesulide.The short-term curative effect of three groups were compared and analyzed.Results The total effective rate of pain relief in group A 3 days after treatment was 53.13%,and that of group B and group C were 65.63% and 90.63% respectively.The efficacy of pain relief in group C was significantly better than that of group A and group B(P<0.05),and there was no significant difference the efficacy of pain relief between group A and group B(P>0.05).The adverse reaction ratio of group A,B and C were 3.13%,0 and 3.13% respectively 1 week after treatment.There was 1 case of stomach upset in group A,0 case in group B, and 1 case in group C without any other adverse reactions.There were no significant difference among the three groups (P>0.05).The coagulations indicators of all the three groups were normal.Conclusion The curative effect of fenbid short-term combined with nimesulide in the treatment of patients with pain is significant without any adverse reaction, which can be applied as short-term therapy.
