CAJ | 학술논문

目的：探讨抗血小板药物联合低分子肝素在糖尿病合并脑梗死中的疗效。方法以我院325例糖尿病合并脑梗死患者为研究对象，将其随机分成两组，A组（160例）联合奥扎格雷、低分子肝素治疗，B组（165例）联合氯吡格雷、低分子肝素治疗,比较两组的临床疗效。结果 A组治疗3个月后总有效率83.75%， B组总有效率92.12%，组间比较差异显著（P＜0.05）；A组NIHSS评分（9.2±2.6）分，B组NIHSS评分（7.2±2.3）分，组间比较差异有统计学意义（P＜0.05）。结论相较于奥扎格雷，氯吡格雷联合低分子肝素治疗糖尿病合并脑梗死的疗效更佳，值得临床应用。
목적：탐토항혈소판약물연합저분자간소재당뇨병합병뇌경사중적료효。방법이아원325례당뇨병합병뇌경사환자위연구대상，장기수궤분성량조，A조（160례）연합오찰격뢰、저분자간소치료，B조（165례）연합록필격뢰、저분자간소치료,비교량조적림상료효。결과 A조치료3개월후총유효솔83.75%， B조총유효솔92.12%，조간비교차이현저（P＜0.05）；A조NIHSS평분（9.2±2.6）분，B조NIHSS평분（7.2±2.3）분，조간비교차이유통계학의의（P＜0.05）。결론상교우오찰격뢰，록필격뢰연합저분자간소치료당뇨병합병뇌경사적료효경가，치득림상응용。
Objective To investigate the effect of antiplatelet drugs combined with low molecular weight heparin in the treatment of diabetes complicated with cerebral infarction.Methods 325 cases of patients with diabetes complicated with cerebral infarction were selected as research object in our hospital. They were divided into 2 groups randomLy. Ozagrel combined with low molecular weight heparin was used to treat group A (160 cases). Clopidogrel combined with low molecular weight heparin was used to treat group B (165 cases). The clinical effect between the two groups was then compared.Results After treatment of 3 months, total efficiency of group A was 83.64%, and that of the group B was 92.17%. There was significant difference between the two groups(P<0.05). The NIHSS score of group A was (9.2±2.6) points, and the group B was(7.2±2.3)points. There was significant difference between groups(P<0.05).Conclusion Compared with ozagrel, clopidogrel combined with low molecular heparin has a better effect in the treatment of diabetes complicated with cerebral infarction, which is worthy of application.