中国医药科学
中國醫藥科學
중국의약과학
CHINA MEDICINE AND PHARMACY
2015年
8期
64-66
,共3页
儿科监护病房%感染性疾病%降钙素原
兒科鑑護病房%感染性疾病%降鈣素原
인과감호병방%감염성질병%강개소원
PICU%Infectious diseases%PCT
目的：探讨降钙素原对PICU感染性疾病患者预后的预测价值。方法回顾性分析236例感染性危重病患儿的临床资料，分析患者降钙素原水平与预后的关系。结果236例患儿治愈215例，占87.4%，21例患儿死亡，占8.9%。死亡组≥10ng/mL 的比例显著高于治愈组（P＜0.01）。Spearman相关分析结果显示PCT水平与APACHE Ⅱ呈正相关（r=0.731，P＜0.01）。以≥10ng/mL为界值的约登指数最大，说明以≥10ng/mL的预测价值相对较高。结论 PICU感染性疾病患儿PCT水平与入住PICU时APACHE Ⅱ评分呈显著正相关，死亡患儿PCT水平≥10ng/mL的比例显著高于治愈患儿，以≥10ng/mL为界值对患儿预后的预测价值相对较高。
目的：探討降鈣素原對PICU感染性疾病患者預後的預測價值。方法迴顧性分析236例感染性危重病患兒的臨床資料，分析患者降鈣素原水平與預後的關繫。結果236例患兒治愈215例，佔87.4%，21例患兒死亡，佔8.9%。死亡組≥10ng/mL 的比例顯著高于治愈組（P＜0.01）。Spearman相關分析結果顯示PCT水平與APACHE Ⅱ呈正相關（r=0.731，P＜0.01）。以≥10ng/mL為界值的約登指數最大，說明以≥10ng/mL的預測價值相對較高。結論 PICU感染性疾病患兒PCT水平與入住PICU時APACHE Ⅱ評分呈顯著正相關，死亡患兒PCT水平≥10ng/mL的比例顯著高于治愈患兒，以≥10ng/mL為界值對患兒預後的預測價值相對較高。
목적：탐토강개소원대PICU감염성질병환자예후적예측개치。방법회고성분석236례감염성위중병환인적림상자료，분석환자강개소원수평여예후적관계。결과236례환인치유215례，점87.4%，21례환인사망，점8.9%。사망조≥10ng/mL 적비례현저고우치유조（P＜0.01）。Spearman상관분석결과현시PCT수평여APACHE Ⅱ정정상관（r=0.731，P＜0.01）。이≥10ng/mL위계치적약등지수최대，설명이≥10ng/mL적예측개치상대교고。결론 PICU감염성질병환인PCT수평여입주PICU시APACHE Ⅱ평분정현저정상관，사망환인PCT수평≥10ng/mL적비례현저고우치유환인，이≥10ng/mL위계치대환인예후적예측개치상대교고。
Objective To discuss predictive value of PCT detection for prognosis of children with infectious diseases in PICU. Methods Clinical data of 236 cases with infectious diseases in PICU were retrospectively analyzed. Relationship of PCT leves and prognosis was analyzed. Results Of 236 cases, 215 cases cured, accounting for 87.4%, and 21 cases were death, accounting for 8.9%. Proportion of PCT ≥ 10ng/mL of death group was higher than cure group(P<0.01). Spearman results showed PCT was positive correlation with APACHEⅡ(r=0.731,P<0.01). Cutoff value of ≥10 ng/mL was maximum Youden index, which predictive value was relatively high. Conclusion PCT of children with infectious diseases in PICU is positive correlation with APACHEⅡ, proportion of PCT≥10ng/mL of death group is higher than cure group, and ≥10ng/mL predictive value is relatively high.
