临床和实验医学杂志
臨床和實驗醫學雜誌
림상화실험의학잡지
JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE
2015年
9期
761-763
,共3页
不孕症%肾虚型%卵泡发育不良%益肾调冲%子宫内膜容受性
不孕癥%腎虛型%卵泡髮育不良%益腎調遲%子宮內膜容受性
불잉증%신허형%란포발육불량%익신조충%자궁내막용수성
Infertility%Kidney - deficiency type%Follicular maldevelopment%Tonifying kidney and regulating chong%Endometrial recep-tivity
目的：观察益肾调冲中药对卵泡发育不良肾虚型不孕症患者的卵泡发育及子宫内膜容受性的影响。方法将卵泡发育不良肾虚型不孕症患者60例随机分为治疗组30例和对照组30例，治疗组予益肾调冲中药加克罗米芬治疗，对照组予克罗米芬治疗。共治疗3个月经周期。观察两组治疗后优势卵泡发育率、周期排卵率、单卵泡周期排卵率、子宫内膜形态、子宫内膜厚度、子宫动脉血流阻力指数等指标。结果治疗组周期排卵率、单卵泡周期排卵率、子宫内膜形态、子宫内膜厚度、子宫动脉血流阻力指数明显优于对照组（ P <0.05）。结论益肾调冲中药可改善卵泡发育不良肾虚型不孕症患者的子宫动脉血流灌注，促进子宫内膜形态及厚度发育，改善子宫内膜容受性，促进卵泡发育、排出，提高单卵泡周期排卵率，减少单用西药的不良反应。
目的：觀察益腎調遲中藥對卵泡髮育不良腎虛型不孕癥患者的卵泡髮育及子宮內膜容受性的影響。方法將卵泡髮育不良腎虛型不孕癥患者60例隨機分為治療組30例和對照組30例，治療組予益腎調遲中藥加剋囉米芬治療，對照組予剋囉米芬治療。共治療3箇月經週期。觀察兩組治療後優勢卵泡髮育率、週期排卵率、單卵泡週期排卵率、子宮內膜形態、子宮內膜厚度、子宮動脈血流阻力指數等指標。結果治療組週期排卵率、單卵泡週期排卵率、子宮內膜形態、子宮內膜厚度、子宮動脈血流阻力指數明顯優于對照組（ P <0.05）。結論益腎調遲中藥可改善卵泡髮育不良腎虛型不孕癥患者的子宮動脈血流灌註，促進子宮內膜形態及厚度髮育，改善子宮內膜容受性，促進卵泡髮育、排齣，提高單卵泡週期排卵率，減少單用西藥的不良反應。
목적：관찰익신조충중약대란포발육불량신허형불잉증환자적란포발육급자궁내막용수성적영향。방법장란포발육불량신허형불잉증환자60례수궤분위치료조30례화대조조30례，치료조여익신조충중약가극라미분치료，대조조여극라미분치료。공치료3개월경주기。관찰량조치료후우세란포발육솔、주기배란솔、단란포주기배란솔、자궁내막형태、자궁내막후도、자궁동맥혈류조력지수등지표。결과치료조주기배란솔、단란포주기배란솔、자궁내막형태、자궁내막후도、자궁동맥혈류조력지수명현우우대조조（ P <0.05）。결론익신조충중약가개선란포발육불량신허형불잉증환자적자궁동맥혈류관주，촉진자궁내막형태급후도발육，개선자궁내막용수성，촉진란포발육、배출，제고단란포주기배란솔，감소단용서약적불량반응。
Objective To observe the influence of tonifying kidney and regulating chong traditional Chinese medicine on follicular devel-opment and endometrial receptivity in kidney - deficiency infertile patients with follicuiar maldevelopment. Methods Sixty infertile patients with follicular maldevelopment and kidney deficiency were divided into treatment group(n = 30)and control group(n = 30). The treatment group was treated with tonifying kidney and regulating chong traditional Chinese medicine and clomiphene citrate,the control group was treated with clomi-phene citrate only. The dominant follicle development rate,cycle ovulation rate,single follicle cycle ovulation rate,the morphology and thickness of endometrium,and uterine artery resistance index were observed. Results In the treatment group,the cycle ovulation rate,single follicle cycle ovulation rate,morphology and thickness of endometrium,and uterine artery resistance index were significantly better than the control group(all P< 0. 05). Conclusion Tonifying kidney and regulating chong traditional Chinese medicine can improve the uterine artery blood flow perfusion, promote the development of endometrial morphology and thickness,improve the endometrial receptivity,promote follicular development and dis-charge,improve single follicle cycle ovulation rate,and reduce side effects of Western medicine alone.
