中国组织工程研究
中國組織工程研究
중국조직공정연구
Journal of Clinical Rehabilitative Tissue Engineering Research
2015年
18期
2896-2900
,共5页
高君%王维%那磊%姜洪涛%刘士波%高云峰%王培
高君%王維%那磊%薑洪濤%劉士波%高雲峰%王培
고군%왕유%나뢰%강홍도%류사파%고운봉%왕배
实验动物%组织移植动物模型%腱周膜%肌腱损伤%肌腱粘连%移植
實驗動物%組織移植動物模型%腱週膜%肌腱損傷%肌腱粘連%移植
실험동물%조직이식동물모형%건주막%기건손상%기건점련%이식
tenotomy%transplantation%tissue adhesion
背景:肌腱修复术后肌腱与周围组织的粘连问题一直是临床工作中难以解决的问题之一。<br> 目的:构建雌性来亨鸡制备双爪第3趾趾深屈肌腱横断模型,研究腱周膜移植对预防肌腱术后粘连的作用。方法:造模成功后,左爪第3趾为实验组1,肌腱切断后缝合,取鸡同侧第4趾趾深屈肌腱腱周膜包绕实验组1肌腱吻合端,左爪第4趾为实验组2直接缝合皮肤。右爪第3趾为对照组1,肌腱切断后缝合,不修复腱周膜;右爪第4趾手术不损伤腱周膜为对照组2,肌腱进行大体观察和组织学观察。<br> 结果与结论:术后28 d,来亨鸡肌腱大体观察及组织学观察采用Kruskal-Wal isH和 Nemenyi检验两两比较,实验组1术后效果优于对照组1(P <0.05),但较对照组2及实验组2略差(P <0.05);实验组2术后效果优于对照组1组(P<0.05),与对照组2比较,差异不显著(P>0.05)。屈趾功能采用LSD-t检验两两比较,实验组1术后效果优于对照组1(P <0.05),但较对照组2及实验组2略差(P <0.05),实验组2术后效果优于对照组1(P<0.05),与对照组2比较,差异不显著(P>0.05)。结果提示,腱周膜移植可以有效预防术后肌腱粘连,切取腱周膜对正常肌腱滑动影响不大。
揹景:肌腱脩複術後肌腱與週圍組織的粘連問題一直是臨床工作中難以解決的問題之一。<br> 目的:構建雌性來亨鷄製備雙爪第3趾趾深屈肌腱橫斷模型,研究腱週膜移植對預防肌腱術後粘連的作用。方法:造模成功後,左爪第3趾為實驗組1,肌腱切斷後縫閤,取鷄同側第4趾趾深屈肌腱腱週膜包繞實驗組1肌腱吻閤耑,左爪第4趾為實驗組2直接縫閤皮膚。右爪第3趾為對照組1,肌腱切斷後縫閤,不脩複腱週膜;右爪第4趾手術不損傷腱週膜為對照組2,肌腱進行大體觀察和組織學觀察。<br> 結果與結論:術後28 d,來亨鷄肌腱大體觀察及組織學觀察採用Kruskal-Wal isH和 Nemenyi檢驗兩兩比較,實驗組1術後效果優于對照組1(P <0.05),但較對照組2及實驗組2略差(P <0.05);實驗組2術後效果優于對照組1組(P<0.05),與對照組2比較,差異不顯著(P>0.05)。屈趾功能採用LSD-t檢驗兩兩比較,實驗組1術後效果優于對照組1(P <0.05),但較對照組2及實驗組2略差(P <0.05),實驗組2術後效果優于對照組1(P<0.05),與對照組2比較,差異不顯著(P>0.05)。結果提示,腱週膜移植可以有效預防術後肌腱粘連,切取腱週膜對正常肌腱滑動影響不大。
배경:기건수복술후기건여주위조직적점련문제일직시림상공작중난이해결적문제지일。<br> 목적:구건자성래형계제비쌍조제3지지심굴기건횡단모형,연구건주막이식대예방기건술후점련적작용。방법:조모성공후,좌조제3지위실험조1,기건절단후봉합,취계동측제4지지심굴기건건주막포요실험조1기건문합단,좌조제4지위실험조2직접봉합피부。우조제3지위대조조1,기건절단후봉합,불수복건주막;우조제4지수술불손상건주막위대조조2,기건진행대체관찰화조직학관찰。<br> 결과여결론:술후28 d,래형계기건대체관찰급조직학관찰채용Kruskal-Wal isH화 Nemenyi검험량량비교,실험조1술후효과우우대조조1(P <0.05),단교대조조2급실험조2략차(P <0.05);실험조2술후효과우우대조조1조(P<0.05),여대조조2비교,차이불현저(P>0.05)。굴지공능채용LSD-t검험량량비교,실험조1술후효과우우대조조1(P <0.05),단교대조조2급실험조2략차(P <0.05),실험조2술후효과우우대조조1(P<0.05),여대조조2비교,차이불현저(P>0.05)。결과제시,건주막이식가이유효예방술후기건점련,절취건주막대정상기건활동영향불대。
BACKGROUND:The adhesion between muscle tendon and surrounding tissue after tendon restoration is one hot topic in clinic. <br> OBJECTIVE:To construct a deep flexor tendon transection model in the third toe of female Leghorn chicken and to explore the effect of peritenon transplantation on the prevention of tendon adhesions. <br> METHODS:After the transection models were successful y established, the third toe of left claw was taken as experimental group A. The transected tendon was sutured, the tendon anastomosis end was wrapped with the peritenon of the deep flexor tendon from the ipsilateral fourth toe (experimental group B). The third toe of right claw served as control group A, the transfected tendon was sutured and restored with the peritenon. The fourth toe of right claw was taken as control group B. Gross observation and histological observation of the tendon were performed. <br> RESULTS AND CONCLUSION:At 28 days postoperatively, gross observation and histological observation of Leghorn chicken were performed and compared using the Kruskal-Wal isH and Nemenyi test, respectively. The results showed that, the therapeutic effect was better in experimental group A than in control group A (P<0.05), but slightly poorer compared with control group B and experimental group B (P<0.05). The postoperative effect was better in experimental group B than in control group A (P<0.05) and showed no significant difference between experimental group B and control group B (P>0.05). The flexor function was evaluated and compared with the least significant difference t-test. The results showed that the postoperative effect was better in experimental group A than in control group A (P<0.05), but slightly poorer compared with control group B and experimental group B (P<0.05). The postoperative effect was better in experimental group B than in control group A (P<0.05) and showed no significant difference compared with control group B (P>0.05). Peritenon transplantation can effectively prevent tendon adhesions and has little impact on normal tendon sliding.