中国肿瘤临床
中國腫瘤臨床
중국종류림상
CHINESE JOURNAL OF CLINICAL ONCOLOGY
2015年
9期
466-470
,共5页
高红梅%肖国伟%池书平%沈文斌
高紅梅%肖國偉%池書平%瀋文斌
고홍매%초국위%지서평%침문빈
食管癌%放疗%化疗%临床无转移%淋巴结转移
食管癌%放療%化療%臨床無轉移%淋巴結轉移
식관암%방료%화료%림상무전이%림파결전이
esophageal cancer%radiotherapy%chemotherapy%no-metastasis%lymph node metastasis
目的：分析可能影响临床无转移食管鳞癌患者接受根治性放（化）疗后出现淋巴结转移的因素。方法：选取2002年1月至2009年12月于河北医科大学第四医院放疗科接受治疗的263例食管鳞癌患者，分析患者一般临床资料及肿瘤局部因素中可能影响患者治疗后出现淋巴结转移的因素。结果：全组263例食管癌患者治疗后出现淋巴结转移31例（11.8%），其中18例为单纯淋巴结转移，余13例淋巴结转移患者伴有其他脏器转移和（或）食管复发。胸上段、胸中段及胸下段食管癌患者淋巴结转移分别为11例（13.3%）、13例（10.1%）及7例（13.7%）。单因素分析结果显示患者近期疗效、食管病变造影长度、病变最大横径及病变体积为影响患者治疗后出现淋巴结失败的因素（χ2=7.597、9.717、5.361、4.815；P=0.006、0.002、0.021、0.028）；Logistic多因素分析结果显示食管病变造影长度及近期疗效为患者治疗后出现淋巴结转移的独立影响因素（P=0.004、0.026）。结论：食管病变造影长度及即时疗效为影响临床无转移食管鳞癌患者接受根治性放（化）疗后出现淋巴结转移的主要因素。
目的：分析可能影響臨床無轉移食管鱗癌患者接受根治性放（化）療後齣現淋巴結轉移的因素。方法：選取2002年1月至2009年12月于河北醫科大學第四醫院放療科接受治療的263例食管鱗癌患者，分析患者一般臨床資料及腫瘤跼部因素中可能影響患者治療後齣現淋巴結轉移的因素。結果：全組263例食管癌患者治療後齣現淋巴結轉移31例（11.8%），其中18例為單純淋巴結轉移，餘13例淋巴結轉移患者伴有其他髒器轉移和（或）食管複髮。胸上段、胸中段及胸下段食管癌患者淋巴結轉移分彆為11例（13.3%）、13例（10.1%）及7例（13.7%）。單因素分析結果顯示患者近期療效、食管病變造影長度、病變最大橫徑及病變體積為影響患者治療後齣現淋巴結失敗的因素（χ2=7.597、9.717、5.361、4.815；P=0.006、0.002、0.021、0.028）；Logistic多因素分析結果顯示食管病變造影長度及近期療效為患者治療後齣現淋巴結轉移的獨立影響因素（P=0.004、0.026）。結論：食管病變造影長度及即時療效為影響臨床無轉移食管鱗癌患者接受根治性放（化）療後齣現淋巴結轉移的主要因素。
목적：분석가능영향림상무전이식관린암환자접수근치성방（화）료후출현림파결전이적인소。방법：선취2002년1월지2009년12월우하북의과대학제사의원방료과접수치료적263례식관린암환자，분석환자일반림상자료급종류국부인소중가능영향환자치료후출현림파결전이적인소。결과：전조263례식관암환자치료후출현림파결전이31례（11.8%），기중18례위단순림파결전이，여13례림파결전이환자반유기타장기전이화（혹）식관복발。흉상단、흉중단급흉하단식관암환자림파결전이분별위11례（13.3%）、13례（10.1%）급7례（13.7%）。단인소분석결과현시환자근기료효、식관병변조영장도、병변최대횡경급병변체적위영향환자치료후출현림파결실패적인소（χ2=7.597、9.717、5.361、4.815；P=0.006、0.002、0.021、0.028）；Logistic다인소분석결과현시식관병변조영장도급근기료효위환자치료후출현림파결전이적독립영향인소（P=0.004、0.026）。결론：식관병변조영장도급즉시료효위영향림상무전이식관린암환자접수근치성방（화）료후출현림파결전이적주요인소。
Objective:To analyze the factors affecting lymph node failure pattern after radiotherapy/chemotherapy in esophageal squamous cell carcinoma without initial clinical metastasis. Methods:A total of 263 patients, who were diagnosed as thoracic esopha-geal carcinoma from January 2002 to December 2009, were included in this retrospective study. Factors affecting lymph node failure pattern with general clinical data and tumor local factors were analyzed. Results:Among the 263 esophageal cancer cases, 31 (11.8%) had lymph node metastasis after treatment, including 18 cases of simple lymph node metastasis and 13 other cases of lymph node metas-tasis with esophageal and other organ metastasis or recurrence. The numbers of cases for lymph node metastasis in the upper, middle, and lower thoracic esophagus were 11 (13.3%), 13 (10.1%), and 7 (13.7%), respectively. Univariate analysis showed that recent cura-tive effect, length of tumor on X-rays, maximum tumor diameter, and tumor volume were the significant factors associated with lymph node metastasis (χ2=7.597, 9.717, 5.361, and 4.815;P=0.006, 0.002, 0.021, and 0.028). Logistic regression analysis results showed that recent curative effect and length of tumor on X-rays were independent significant factors (P=0.004 and 0.026). Conclusion:Recent cu-rative effect and length of tumor on X-rays were the significant factors associated with lymph node failure pattern after radiotherapy/chemotherapy in esophageal squamous cell carcinoma without initial clinical metastasis.
