CAJ | 학술논문

以聚乙二醇-600为反应介质，在CuSO4/葡萄糖催化作用下，取代苯胺与硫脲有效缩合生成了一系列相应的苯基硫脲。反应产物经水洗、过滤、乙醇/水中重结晶即可获得。该方法不使用有毒有机溶剂，原料及催化剂价廉，后处理简单便捷，因此是合成该类化合物高效绿色的新方法。所有产物经熔点、红外、核磁共振氢谱进行了表征。
이취을이순-600위반응개질，재CuSO4/포도당최화작용하，취대분알여류뇨유효축합생성료일계렬상응적분기류뇨。반응산물경수세、과려、을순/수중중결정즉가획득。해방법불사용유독유궤용제，원료급최화제개렴，후처리간단편첩，인차시합성해류화합물고효록색적신방법。소유산물경용점、홍외、핵자공진경보진행료표정。
A series of diphenylthioureas were efficiently synthesized through condensation of anilines with thiourea catalyzed by Cu-SO4/glucose in PEG-600. The products were obtained just by washing with water, filtration and recrystallization from EtOH/H2 O. The present method exhibited the following advantages:free use of toxic organic solvent,cheap starting materials and catalyst, and simple work-up procedure. These merits made it an efficient and green alternative to synthesis of diphenylthioureas. All the products were characterized with m. p. ,IR and 1 H-NMR analysis.