CAJ | 학술논문

目的：探讨盐酸特比萘芬乳膏和硝酸咪康唑乳膏治疗皮肤癣菌感染的临床疗效。方法选择该院2011年6月至2013年6月收治的200例皮肤癣菌感染患者，随机分为试验组和对照组，每组各100例。试验组患者使用盐酸特比萘酚乳膏涂抹于患处，每天2次，早晚各1次；对照组患者使用硝酸咪康唑乳膏涂抹患处，每天1次。手癣、体股癣及严重者的治疗疗程分别为2、4、6周。疗程结束后，对两组患者的临床疗效进行比较。结果试验组患者的临床有效率（90．62％）和痊愈率（83．12％）明显高于对照组患者（78．25％和63．25％），差异有统计学意义（P＜0．05）。结论盐酸特比萘酚乳膏治疗皮肤癣菌感染疗效优于硝酸咪康唑乳膏，安全性好。
목적：탐토염산특비내분유고화초산미강서유고치료피부선균감염적림상료효。방법선택해원2011년6월지2013년6월수치적200례피부선균감염환자，수궤분위시험조화대조조，매조각100례。시험조환자사용염산특비내분유고도말우환처，매천2차，조만각1차；대조조환자사용초산미강서유고도말환처，매천1차。수선、체고선급엄중자적치료료정분별위2、4、6주。료정결속후，대량조환자적림상료효진행비교。결과시험조환자적림상유효솔（90．62％）화전유솔（83．12％）명현고우대조조환자（78．25％화63．25％），차이유통계학의의（P＜0．05）。결론염산특비내분유고치료피부선균감염료효우우초산미강서유고，안전성호。
Objective To investigate the clinical efficacy of terbinafine hydrochloride cream and miconazole ni‐trate cream in treating dermatophyte infections .Methods A total of 200 patients with dermatophyte infections were recruited in this study from June 2011 to June 2013 ,and divided into the experimental group and the control group randomly ,100 cases in each group .Patients in the experimental group treated with terbinafine hydrochloride cream for external use ,2 times a day ,one in the morning and the other in the evening .Patients in the control group treated with miconazole nitrate cream for external use ,1 times a day .The course of treatment of serve patients and patients with tinea manuum ,tinea corporis and cruris were 6 ,2 ,4 weeks .After treatment ,the clinical efficacy of the two groups were compared .Results The clinical effective rate and cure rate were 90 .62% and 83 .12% in the experi‐mental group ,which were significant higher than 78 .25% and 63 .25% in the control group ,and the differences were statistically significant (P<0 .05) .Conclusion Phenol terbinafine hydrochloride cream with good security is superi‐or to miconazole nitrate cream in treatment of dermatophyte infections .