CAJ | 학술논문

目的：观察山香圆颗粒联合抗病毒颗粒治疗小儿急性上呼吸道感染的临床疗效和安全性观察。方法：将812例急性上呼吸道感染患儿随机分组，其中治疗组406例，给予山香圆颗粒联合抗病毒颗粒治疗；对照组406例，给予抗病毒颗粒治疗；疗程均为3d。观察两组患儿临床治疗效果以及不良反应情况。并对比其流涕及鼻塞停止时间、退热时间、咽部充血消失时间以及咳嗽停止时间。结果：治疗组各项临床时间指标均短于对照组，差异具有统计学意义（ P＜0．05）；两组患儿治疗过程中及治疗后均无不良反应发生；治疗组总有效率为91．6％，高于对照组的78．3％，差异显著（ P＜0．05）。结论：山香圆颗粒联合抗病毒颗粒治疗小儿急性上呼吸道感染安全性较高，临床疗效显著，无不良反应情况发生，值得临床推广应用。
목적：관찰산향원과립연합항병독과립치료소인급성상호흡도감염적림상료효화안전성관찰。방법：장812례급성상호흡도감염환인수궤분조，기중치료조406례，급여산향원과립연합항병독과립치료；대조조406례，급여항병독과립치료；료정균위3d。관찰량조환인림상치료효과이급불량반응정황。병대비기류체급비새정지시간、퇴열시간、인부충혈소실시간이급해수정지시간。결과：치료조각항림상시간지표균단우대조조，차이구유통계학의의（ P＜0．05）；량조환인치료과정중급치료후균무불량반응발생；치료조총유효솔위91．6％，고우대조조적78．3％，차이현저（ P＜0．05）。결론：산향원과립연합항병독과립치료소인급성상호흡도감염안전성교고，림상료효현저，무불량반응정황발생，치득림상추엄응용。
Objective:To observe the clinical efficacy and safety of turpinia particles combined antiviral granules in treatment of children with acute upper respiratory tract infection .Methods:812 cases of upper re-spiratory tract infection were randomly divided into treatment group and control group .406 patients in treat-ment group were treated with turpinia particles combined antiviral granules , while 406patients in control group were given antiviral granules , 3 days for a course of treatment , both groups were cured for 3 days. To compared the disappeared time of fever , cough, stuffy nose, sore throat, pharyngeal hyperemia, adverse re-actions,clinical efficacy.Result: The disappeared time of clinical symptoms of treatment group was signifi-cantly less than the control group ( P<0.05); There were no adverse reactions in both of two groups .The cured rate in treatment group were significantly higher than the control group (P<0.05).Conclusion: The turpinia particles combined antiviral granules has a good effect in treatment of children with acute upper re -spiratory tract infection , there's no adverse reactions in both of two groups , which is appropriate to use in clinical.