CAJ | 학술논문

目的建立多中心血糖检测电子化质量监控系统,为大规模流行病学调查中多地区血糖和其他指标实验室检测质控系统的建立提供借鉴.方法在中国慢性病及其危险因素监测项目中,利用电子信息化技术建立基于网络的血糖检测质量控制系统,包括血糖检测实验室性能验证数据、血糖检测实时质控数据输入、传输和质量评估反馈,对302个监测点血糖检测质量和有效性进行评估.结果参与该项目的所有监测点,满足了质量要求并成功地完成了血糖重复性精密度监测初步评估.仅有少数监测点需要强化训练和重新进行中间精密度检测性能评估.从各监测点每日质控的数据分析来看,绝大部分监测点实验室所采用的血糖监测系统具有良好的室内重复性.结论为确保多中心的血糖数据的完整性和可靠性,电子化血糖质控系统的建立和适当质量保证程序可以帮助识别监测点是否可以满足室内精密度质量标准,确保其能够胜任血糖实验室检测工作,及时评估各地区血糖检测的质量;同时发现,实验室人员的培训和有效沟通非常重要.后续可以根据研究项目的需要增加并完善监控系统的功能,降低因使用不同血糖检测方法导致的室间分析偏倚.
목적 건립다중심혈당검측전자화질량감공계통,위대규모류행병학조사중다지구혈당화기타지표실험실검측질공계통적건립제공차감.방법 재중국만성병급기위험인소감측항목중,이용전자신식화기술건립기우망락적혈당검측질량공제계통,포괄혈당검측실험실성능험증수거、혈당검측실시질공수거수입、전수화질량평고반궤,대302개감측점혈당검측질량화유효성진행평고.결과 삼여해항목적소유감측점,만족료질량요구병성공지완성료혈당중복성정밀도감측초보평고.부유소수감측점수요강화훈련화중신진행중간정밀도검측성능평고.종각감측점매일질공적수거분석래간,절대부분감측점실험실소채용적혈당감측계통구유량호적실내중복성.결론 위학보다중심적혈당수거적완정성화가고성,전자화혈당질공계통적건립화괄당질량보증정서가이방조식별감측점시부가이만족실내정밀도질량표준,학보기능구성임혈당실험실검측공작,급시평고각지구혈당검측적질량;동시발현,실험실인원적배훈화유효구통비상중요.후속가이근거연구항목적수요증가병완선감공계통적공능,강저인사용불동혈당검측방법도치적실간분석편의.
Objective The aim of this paper is to describe the designing and implementation of a web-based plasma glucose measurement quality monitoring system to assess the analytical quality of plasma glucose measurements in multicenter population study and provide evidence for the future studies.Methods In the chronic non-communicable disease and related factor surveillance in China,a web based quality monitoring system for plasma glucose measurement was established to conduct evaluation on plasma glucose monitoring quality and effectiveness in 302 surveillance centers,including quality control data entry,transmission and feedback.Results The majority of the surveillance centers met the quality requirements and passed the evaluation of reproducibility and precision of plasma glucose measurement,only a few centers required intensive training and re-assessment.Conclusion In order to ensure the completeness and reliability of plasma glucose measurement in the surveillance centers,the establishment of web-based plasma glucose measurement quality control system can facilitate the identification of the qualified surveillance centers and evaluation of plasma glucose measurement quality in different regions.Communication and training are important in ensuring plasma glucose measurement quality.It is necessary to further improve this web-based plasma glucose measurement quality monitoring system in the future to reduce the method specific plasma glucose measurement bias.