中国实用眼科杂志
中國實用眼科雜誌
중국실용안과잡지
CHINESE JOURNAL OF PRACTICAL OPHTHALMOLOGY
2015年
4期
358-361
,共4页
冯程程%孙艳%刘菲%邓爱军
馮程程%孫豔%劉菲%鄧愛軍
풍정정%손염%류비%산애군
频域光学相干断层扫描%特发性黄斑裂孔%脉络膜厚度
頻域光學相榦斷層掃描%特髮性黃斑裂孔%脈絡膜厚度
빈역광학상간단층소묘%특발성황반렬공%맥락막후도
Spectral-domain optical coherence tomography%Idiopathic macular holes%Choroidal thickness
目的 探讨特发性黄斑裂孔(IMH)患眼手术前后黄斑中心凹脉络膜厚度(SFCT),及其与术前、术后最佳矫正视力的相关性.方法 临床病例对照研究.对2013年1月至2014年1月在潍坊医学院附属医院眼科中心就诊的单眼IMH患者共24例(24只眼),并纳入24名性别、年龄相匹配的正常对照者,采用频域光学相干断层扫描技术测量IMH患眼与正常对照眼SFCT及中心凹鼻侧、颞侧、上方和下方1mm处共5个位点的脉络膜厚度.并分析患眼术前、术后最佳矫正视力与术前SFCT的相关性.结果 IMH患眼组、IMH患者对侧健眼、正常对照组的SFCT均值分别为(190.63±28.33)、(221.52±24.63)、(254.21±22.99) μm,方差分析显示三组间所有位点的脉络膜厚度差异均有统计学意义[SFCT (F =4.08,P=0.032)、NCT1mm (F =3.97,P=0.041)、TCT1mm (F =4.21,P=0.034)、SCT1mm (F =4.03,P=0.027)、ICT1mm(F=4.57,P=0.046)].进一步行SNK检验,IMH患眼各位点的脉络膜厚度值均较正常对照组显著降低,差异有统计学意义,[SFCT (q =3.68,P=0.037)、NCT1mm (q =4.04,P=0.021)、TCT1mm(q=4.12,P=0.041)、SCT1mm(q=3.86,P=0.025),ICT1mm(q=4.21,P=0.029)].IMH对侧健眼与正常对照组仅SFCT差异有统计学意义(q=4.02,P =0.033).术前SFCT与术前、术后最佳矫正视力差异无统计学意义(r=0.306,P=0.073;r=0.268,P=0.078).结论 IMH患者患眼的脉络膜厚度明显变薄,提示脉络膜厚度变薄与IMH的发生可能存在一定关系,而与患者最佳矫正视力无相关性.
目的 探討特髮性黃斑裂孔(IMH)患眼手術前後黃斑中心凹脈絡膜厚度(SFCT),及其與術前、術後最佳矯正視力的相關性.方法 臨床病例對照研究.對2013年1月至2014年1月在濰坊醫學院附屬醫院眼科中心就診的單眼IMH患者共24例(24隻眼),併納入24名性彆、年齡相匹配的正常對照者,採用頻域光學相榦斷層掃描技術測量IMH患眼與正常對照眼SFCT及中心凹鼻側、顳側、上方和下方1mm處共5箇位點的脈絡膜厚度.併分析患眼術前、術後最佳矯正視力與術前SFCT的相關性.結果 IMH患眼組、IMH患者對側健眼、正常對照組的SFCT均值分彆為(190.63±28.33)、(221.52±24.63)、(254.21±22.99) μm,方差分析顯示三組間所有位點的脈絡膜厚度差異均有統計學意義[SFCT (F =4.08,P=0.032)、NCT1mm (F =3.97,P=0.041)、TCT1mm (F =4.21,P=0.034)、SCT1mm (F =4.03,P=0.027)、ICT1mm(F=4.57,P=0.046)].進一步行SNK檢驗,IMH患眼各位點的脈絡膜厚度值均較正常對照組顯著降低,差異有統計學意義,[SFCT (q =3.68,P=0.037)、NCT1mm (q =4.04,P=0.021)、TCT1mm(q=4.12,P=0.041)、SCT1mm(q=3.86,P=0.025),ICT1mm(q=4.21,P=0.029)].IMH對側健眼與正常對照組僅SFCT差異有統計學意義(q=4.02,P =0.033).術前SFCT與術前、術後最佳矯正視力差異無統計學意義(r=0.306,P=0.073;r=0.268,P=0.078).結論 IMH患者患眼的脈絡膜厚度明顯變薄,提示脈絡膜厚度變薄與IMH的髮生可能存在一定關繫,而與患者最佳矯正視力無相關性.
목적 탐토특발성황반렬공(IMH)환안수술전후황반중심요맥락막후도(SFCT),급기여술전、술후최가교정시력적상관성.방법 림상병례대조연구.대2013년1월지2014년1월재유방의학원부속의원안과중심취진적단안IMH환자공24례(24지안),병납입24명성별、년령상필배적정상대조자,채용빈역광학상간단층소묘기술측량IMH환안여정상대조안SFCT급중심요비측、섭측、상방화하방1mm처공5개위점적맥락막후도.병분석환안술전、술후최가교정시력여술전SFCT적상관성.결과 IMH환안조、IMH환자대측건안、정상대조조적SFCT균치분별위(190.63±28.33)、(221.52±24.63)、(254.21±22.99) μm,방차분석현시삼조간소유위점적맥락막후도차이균유통계학의의[SFCT (F =4.08,P=0.032)、NCT1mm (F =3.97,P=0.041)、TCT1mm (F =4.21,P=0.034)、SCT1mm (F =4.03,P=0.027)、ICT1mm(F=4.57,P=0.046)].진일보행SNK검험,IMH환안각위점적맥락막후도치균교정상대조조현저강저,차이유통계학의의,[SFCT (q =3.68,P=0.037)、NCT1mm (q =4.04,P=0.021)、TCT1mm(q=4.12,P=0.041)、SCT1mm(q=3.86,P=0.025),ICT1mm(q=4.21,P=0.029)].IMH대측건안여정상대조조부SFCT차이유통계학의의(q=4.02,P =0.033).술전SFCT여술전、술후최가교정시력차이무통계학의의(r=0.306,P=0.073;r=0.268,P=0.078).결론 IMH환자환안적맥락막후도명현변박,제시맥락막후도변박여IMH적발생가능존재일정관계,이여환자최가교정시력무상관성.
Objective To observe the choroidal thickness in eyes with idiopathic macular holes (IMH),unaffected fellow eyes and compare with the normal eyes,and find the correlation between the subfoveal area choroidal thickness and the visual acuity.Methods Twenty-four unilateral IMH patients and 24 age-and sex-matched healthy controls in this research.The choroidal thickness was measured in the subfoveal area and lmm away from the fovea in the nasal,temporal,superior and inferior regions.The IMH eyes' preoperative best correct visual acuity with the postoperative best correct visual acuity was compared.Results The average subfoveal choroidal thickness (SFCT) of IMH eyes was (190.63±28.33)μm,the unaffected fellow eyes was (221.52±24.63)μm,the normal eyes was (254.21±22.99)μm.The SFCT showed significant differences among three groups,SFCT (F =4.08,P =0.032),NCT1mm (F =3.97,P =0.041),TCT1mm (F =4.21,P =0.034),SCT1mm (F =4.03,P =0.027),ICT1mm (F =4.57,P =0.046).The choroidal thickness of all measured regions in IMH eyes had a significantly reduce than the normal eyes,SFCT (q =3.68,P=0.037),NCT1mm (q =4.04,P =0.021),TCT1mm (q =4.12,P =0.041),SCT1mm (q =3.86,P =0.025),ICT1mm (q =4.21,P =0.029).There was a significant difference in SFCT between the unaffected eyes and the normal eyes,(q =4.02,P =0.033).There was no correlation between the SFCT with the preoperative and postoperative best correct visual acuity (r =0.306,P =0.073),(r =0.268,P =0.078).Conclusions The choroidal thickness of IMH patients is thinner than the normal eyes,but has nothing to do with the best correct visual acuity.
