心血管病学进展
心血管病學進展
심혈관병학진전
ADVANCES IN CARDIOVASCULAR DISEASES
2015年
3期
356-359
,共4页
冠状动脉慢血流%发病机制%内皮细胞%炎症
冠狀動脈慢血流%髮病機製%內皮細胞%炎癥
관상동맥만혈류%발병궤제%내피세포%염증
coronary slow flow phenomenon%pathogenesis%endothelial cell%inflammation
冠状动脉慢血流现象是一种由于内皮功能不全引起的微血管功能障碍性疾病。目前认为男性、吸烟、肥胖、高血尿酸水平、糖耐量异常、高血浆同型半胱氨酸水平、血小板功能和形态异常是其致病的高危因素。冠状动脉慢血流现象可能是系统性疾病的一种临床表现，其发病机制尚不清楚，研究提示微血管功能失调及障碍、内皮细胞受损和功能障碍、内皮活化及炎症、基因变异与冠状动脉慢血流现象的发病密切相关。
冠狀動脈慢血流現象是一種由于內皮功能不全引起的微血管功能障礙性疾病。目前認為男性、吸煙、肥胖、高血尿痠水平、糖耐量異常、高血漿同型半胱氨痠水平、血小闆功能和形態異常是其緻病的高危因素。冠狀動脈慢血流現象可能是繫統性疾病的一種臨床錶現，其髮病機製尚不清楚，研究提示微血管功能失調及障礙、內皮細胞受損和功能障礙、內皮活化及炎癥、基因變異與冠狀動脈慢血流現象的髮病密切相關。
관상동맥만혈류현상시일충유우내피공능불전인기적미혈관공능장애성질병。목전인위남성、흡연、비반、고혈뇨산수평、당내량이상、고혈장동형반광안산수평、혈소판공능화형태이상시기치병적고위인소。관상동맥만혈류현상가능시계통성질병적일충림상표현，기발병궤제상불청초，연구제시미혈관공능실조급장애、내피세포수손화공능장애、내피활화급염증、기인변이여관상동맥만혈류현상적발병밀절상관。
Coronary slow flow phenomenon ( CSFP) is a kind of microvascular function disorder caused by endothelial dysfunction. High risk factors for CSFP include smoking, obesity, high blood uric acid level and abnormal glucose tolerance, high plasma homocysteine levels, and abnormal platelet function and form.CSFP may be a single clinical presentation of a systemic disease, however, the pathogenesis of CSFP has not yet been completely understood.Several mechanisms have been proposed for CSFP such as microvascular dysfunction, im-paired endothelial cells, endothelial activation and dysfunction, inflammation, and genetic variation.
