北方药学
北方藥學
북방약학
JOURNAL OF NORTH PHARMACY
2015年
5期
22-23
,共2页
妊娠高血压%拉贝洛尔%临床疗效
妊娠高血壓%拉貝洛爾%臨床療效
임신고혈압%랍패락이%림상료효
Pregnancy induced hypertension%Labetalol%Clinical effect
目的：观察拉贝洛尔治疗妊娠高血压的临床疗效。方法：选取我院在2013～2014年收治的90例妊娠高血压患者为研究对象，随机分为对照组和实验组各45例，对照组给予硫酸镁常规治疗，实验组在对照组治疗的基础上给予拉贝洛尔治疗，对比两组治疗期间的平均收缩压和舒张压、平均24h尿蛋白、并发症及妊娠结局。结果：实验组治疗期间收缩压、舒张压和24h尿蛋白水平分别为（112.51±16.19）mmHg、（80.39±3.28）mmHg、（1.77±0.03）g，显著低于对照组，差异有统计学意义（P<0.05）；实验组胎儿窘迫、新生儿窒息及产后出血发生率均显著低于对照组（P<0.05），差异有统计学意义。胎儿娩出后分别于1min、5min时作Agar评分，分别对比1min、5min时两组新生儿的Agar评分，实验组均显著优于对照组，差异显著（t=4.003，P=0.010），有统计学意义。结论：应用拉贝洛尔治疗妊娠高血压，能有效降低患者的血压，进而降低不良妊娠结局的发生率。
目的：觀察拉貝洛爾治療妊娠高血壓的臨床療效。方法：選取我院在2013～2014年收治的90例妊娠高血壓患者為研究對象，隨機分為對照組和實驗組各45例，對照組給予硫痠鎂常規治療，實驗組在對照組治療的基礎上給予拉貝洛爾治療，對比兩組治療期間的平均收縮壓和舒張壓、平均24h尿蛋白、併髮癥及妊娠結跼。結果：實驗組治療期間收縮壓、舒張壓和24h尿蛋白水平分彆為（112.51±16.19）mmHg、（80.39±3.28）mmHg、（1.77±0.03）g，顯著低于對照組，差異有統計學意義（P<0.05）；實驗組胎兒窘迫、新生兒窒息及產後齣血髮生率均顯著低于對照組（P<0.05），差異有統計學意義。胎兒娩齣後分彆于1min、5min時作Agar評分，分彆對比1min、5min時兩組新生兒的Agar評分，實驗組均顯著優于對照組，差異顯著（t=4.003，P=0.010），有統計學意義。結論：應用拉貝洛爾治療妊娠高血壓，能有效降低患者的血壓，進而降低不良妊娠結跼的髮生率。
목적：관찰랍패락이치료임신고혈압적림상료효。방법：선취아원재2013～2014년수치적90례임신고혈압환자위연구대상，수궤분위대조조화실험조각45례，대조조급여류산미상규치료，실험조재대조조치료적기출상급여랍패락이치료，대비량조치료기간적평균수축압화서장압、평균24h뇨단백、병발증급임신결국。결과：실험조치료기간수축압、서장압화24h뇨단백수평분별위（112.51±16.19）mmHg、（80.39±3.28）mmHg、（1.77±0.03）g，현저저우대조조，차이유통계학의의（P<0.05）；실험조태인군박、신생인질식급산후출혈발생솔균현저저우대조조（P<0.05），차이유통계학의의。태인면출후분별우1min、5min시작Agar평분，분별대비1min、5min시량조신생인적Agar평분，실험조균현저우우대조조，차이현저（t=4.003，P=0.010），유통계학의의。결론：응용랍패락이치료임신고혈압，능유효강저환자적혈압，진이강저불량임신결국적발생솔。
Objective:To study the clinical effect of treatment of pregnancy induced hypertension patients of labetalol. Methods:In our hospital from 2013 to 2014 admitted 90 cases of pregnancy induced hypertension patients as the research object, which were randomly divided into the control group and experimental group with 45 cases in each group, patients in control group were treated with magnesium sulfate routine treatment, patients in the experimental group used Rabelo, based on the treatment in control group, the average shrinkage compared two groups of patients during treatment pressure and diastolic blood pressure, mean 24h urine protein, complications and outcome of pregnancy, statistics processing. Results:In the treatment of patients in the experimental group during the systolic pressure diastolic blood pressure and 24h urine protein level (112.51 ±16.19)/(80.39 ±3.28)mmHg,(1.77 ±0.03)g was significantly lower than the level of control group, with statistical significance (P<0.05); the patients in the experimental group of fetal distress, neonatal asphyxia and the incidence rate of postpartum hemorrhage were significantly lower than that of the control group was statistically significant (P<0.05).After delivery,made Agar score in 1min,.Compared the two groups of neonatal Agar scores in 1min, 5min, the experimental group was significantly better than that of the control group, and the contrast difference is significant (t=4.003, P=0.010), there is statistical significance.Conclusion:The application of labetalol in treatment of pregnancy induced hypertension patients, can effectively reduce the patient's blood pressure levels, thereby reducing the incidence of adverse pregnancy outcome.
