CAJ | 학술논문

急性冠状动脉综合征（ ACS）是以冠状动脉粥样硬化斑块破裂或糜烂，继发完全或不完全闭塞性血栓形成为病理基础的一组临床综合征，它是包括不稳定型心绞痛、非ST段抬高型心肌梗死和ST段抬高型心肌梗死的一系列临床病征。冠状动脉斑块的炎症是导致斑块不稳定，继而诱发ACS的主要因素，其间伴有炎症细胞因子释放，凝血系统激活和血栓形成，心肌细胞坏死及心室压力的改变等。快速而准确地诊断ACS可在早期识别患者并及时给予干预措施，有助于降低不良事件的发生率。现就ACS各病理过程所涉及的研究较多的生物标志物进行分类表述，以期从多方面了解ACS并比较各生物标志物对其的诊断价值。
급성관상동맥종합정（ ACS）시이관상동맥죽양경화반괴파렬혹미란，계발완전혹불완전폐새성혈전형성위병리기출적일조림상종합정，타시포괄불은정형심교통、비ST단태고형심기경사화ST단태고형심기경사적일계렬림상병정。관상동맥반괴적염증시도치반괴불은정，계이유발ACS적주요인소，기간반유염증세포인자석방，응혈계통격활화혈전형성，심기세포배사급심실압력적개변등。쾌속이준학지진단ACS가재조기식별환자병급시급여간예조시，유조우강저불량사건적발생솔。현취ACS각병리과정소섭급적연구교다적생물표지물진행분류표술，이기종다방면료해ACS병비교각생물표지물대기적진단개치。
Acute coronary syndrome ( ACS) is a clinical syndrome for which the pathological basis is a coronary atherosclerotic plaque rupture or erosion, with a secondary complete or incomplete thrombotic occlusion, which also may include a series of clinical symptoms in-cluding unstable angina, non-ST-segment elevation myocardial infarction and ST-segment elevation myocardial infarction.Coronary plaque inflammation is a major factor leading to the plaque instability that causes ACS.The rapid and accurate diagnosis of ACS, combined with timely intervention helps reduce the incidence of adverse events in patients.This review examines the biomarkers involved in the various pathological processes of ACS in order to understand and compare the diagnostic value of those biomarkers in the treatment of ACS.