CAJ | 학술논문

目的：观察四虫化瘤汤联合化疗治疗晚期非小细胞肺癌的临床疗效及毒副反应。方法选取71例晚期非小细胞肺癌患者，随机分为治疗组（四虫化瘤汤联合化疗）（36例）和对照组（单纯化疗）（35例），观察两组间的近期疗效与毒副反应。结果治疗组客观有效率和疾病控制率好于对照组，在疾病控制率方面差异有统计学意义（P＜0．05），毒副反应方面：恶心呕吐、白细胞减少、贫血的发生率治疗组均低于对照组，差异有统计学意义（P＜0．05）。结论四虫化瘤汤联合化疗能增加晚期非小细胞肺癌的疾病控制率并减轻化疗的毒副反应。
목적：관찰사충화류탕연합화료치료만기비소세포폐암적림상료효급독부반응。방법선취71례만기비소세포폐암환자，수궤분위치료조（사충화류탕연합화료）（36례）화대조조（단순화료）（35례），관찰량조간적근기료효여독부반응。결과치료조객관유효솔화질병공제솔호우대조조，재질병공제솔방면차이유통계학의의（P＜0．05），독부반응방면：악심구토、백세포감소、빈혈적발생솔치료조균저우대조조，차이유통계학의의（P＜0．05）。결론사충화류탕연합화료능증가만기비소세포폐암적질병공제솔병감경화료적독부반응。
Objective To observe the efficacy and adverse reactions of Four worm HuaLiu decoction injection plus chemotherapy in the treatment of advanced non-small cell lung cancer( NSCLC) .Methods Seventy-one cases with advanced NSCLC were randomly divided into two groups,36 patients of tested group were treated with Four worm HuaLiu decoction injection combined with chemotherapy and 35 pa-tients of control group were only treated with chemotherapy.The chemotherapy effect,side effects of two groups were evaluated during and after chemotherapy.Results Four worm HuaLiu decoction injection combined with chemotherapy group and the clinical benefit rate was slightly higher than the single chemotherapy group,the difference of the clinical benefit rate was statistically significant(P<0.05).Toxicity of Four worm HuaLiu decoction combined chemotherapy group chemotherapy was lower than the single chemotherapy group,the difference was statis-tically significant(P<0.05),too.Conclusion Four worm HuaLiu decoction injection can improve the curative effect in patients with ad-vanced non-small cell lung cancer,reduce the side effects of chemotherapy and improve the quality of life.