CAJ | 학술논문

目的探讨粗针穿刺活检技术在局部晚期胰腺癌术中病理诊断的应用价值.方法回顾性分析2007年4月至2014年4月在中国医学科学院肿瘤医院住院治疗的局部晚期胰腺癌患者,总结术中行粗针穿刺活检技术患者的临床资料,包括临床特点、病理检查结果和穿刺相关并发症等.术后进行定期随访.结果共入组病例36例.所有均进行粗针穿刺术中病理检查,病理诊断:胰腺癌29例,胰腺神经内分泌肿瘤2例,慢性胰腺炎5例.经随访,5例慢性胰腺炎中1例术后6个月出现肝转移,1例术后4个月出现肝转移,肝转移病灶均穿刺病理证实,结合临床考虑胰腺癌肝转移.其余3例随访＞12个月,肿物大小无变化,无转移灶出现,1例经北京协和医院诊断为自身免疫性胰腺炎,其余2例临床诊断慢性胰腺炎,粗针穿刺准确率94.4％.术后A级胰瘘2例,无出血等并发症发生.结论术中使用粗针穿刺活检技术是局部晚期胰腺癌术中安全有效的病理诊断方法.
목적 탐토조침천자활검기술재국부만기이선암술중병리진단적응용개치.방법 회고성분석2007년4월지2014년4월재중국의학과학원종류의원주원치료적국부만기이선암환자,총결술중행조침천자활검기술환자적림상자료,포괄림상특점、병리검사결과화천자상관병발증등.술후진행정기수방.결과 공입조병례36례.소유균진행조침천자술중병리검사,병리진단:이선암29례,이선신경내분비종류2례,만성이선염5례.경수방,5례만성이선염중1례술후6개월출현간전이,1례술후4개월출현간전이,간전이병조균천자병리증실,결합림상고필이선암간전이.기여3례수방＞12개월,종물대소무변화,무전이조출현,1례경북경협화의원진단위자신면역성이선염,기여2례림상진단만성이선염,조침천자준학솔94.4％.술후A급이루2례,무출혈등병발증발생.결론 술중사용조침천자활검기술시국부만기이선암술중안전유효적병리진단방법.
Objective To explore the application value of core needle biopsy technique in the pathological diagnosis of locally advanced pancreatic cancer patients.Methods During April 2007 to April 2014,retrospective analysis was conducted for 36 patients of locally advanced pancreatic cancer to summarize the clinical data of core needle biopsy technique.And the relevant data included clinical features,pathological findings and puncture-related complications.Regular postoperative follow-ups were conducted.Results All received pathological examination of core needle biopsy.And the pathological diagnoses were pancreatic cancer (n =29),pancreatic neuroendocrine tumors (n =2) and chronic pancreatitis (n =5).During the follow-ups,liver metastasis was pathologically confirmed postoperatively at Months 4 and 6 months among 5 chronic pancreatitis patients.The remainder was followed up for over 12 months.There was neither change in size nor metastasis.One case was diagnosed at Peking Union Hospital as autoimmune pancreatitis while another 2 cases had a clinical diagnosis of chronic pancreatitis.The accuracy of core needle puncture was 94.4％.There were 2 cases of postoperative pancreatic fistula in class A.Bleeding complication was absent.Conclusion The application of core needle biopsy technique is both safe and effective in the pathological diagnosis of locally advanced pancreatic cancer.