中国药业
中國藥業
중국약업
CHINA PHARMACEUTICALS
2015年
9期
93-93,94
,共2页
异丙酚%地佐辛%人工流产%疗效
異丙酚%地佐辛%人工流產%療效
이병분%지좌신%인공유산%료효
propofol%dezocine%artificial abortion%efficacy
目的：观察异丙酚联合不同剂量地佐辛用于人工流产手术中的麻醉作用。方法回顾性分析135例人工流产患者的临床资料，根据手术麻醉使用地佐辛的不同剂量分为低剂量组、中剂量组和高剂量组，各45例，分别给予异丙酚和0.05，0.075，0.10 mg/kg的地佐辛进行麻醉，比较3组患者的麻醉效果、宫缩疼痛视觉模拟评分( VAS评分)以及不良反应发生情况。结果3组患者的总有效率均为100.00%，中剂量组和高剂量组患者的显效率均显著高于低剂量组（ P＜0.05）；术后15，30 min中剂量组和高剂量组患者的宫缩疼痛VAS评分显著低于低剂量组（ P＜0.05）；总不良反应发生率高剂量组患者显著高于低剂量组（ P＜0.05），而中剂量组与低剂量组无显著性差异（ P＞0.05）。结论异丙酚联合0.075 mg/kg地佐辛用于人工流产，麻醉效果好，且不良反应发生率低。
目的：觀察異丙酚聯閤不同劑量地佐辛用于人工流產手術中的痳醉作用。方法迴顧性分析135例人工流產患者的臨床資料，根據手術痳醉使用地佐辛的不同劑量分為低劑量組、中劑量組和高劑量組，各45例，分彆給予異丙酚和0.05，0.075，0.10 mg/kg的地佐辛進行痳醉，比較3組患者的痳醉效果、宮縮疼痛視覺模擬評分( VAS評分)以及不良反應髮生情況。結果3組患者的總有效率均為100.00%，中劑量組和高劑量組患者的顯效率均顯著高于低劑量組（ P＜0.05）；術後15，30 min中劑量組和高劑量組患者的宮縮疼痛VAS評分顯著低于低劑量組（ P＜0.05）；總不良反應髮生率高劑量組患者顯著高于低劑量組（ P＜0.05），而中劑量組與低劑量組無顯著性差異（ P＞0.05）。結論異丙酚聯閤0.075 mg/kg地佐辛用于人工流產，痳醉效果好，且不良反應髮生率低。
목적：관찰이병분연합불동제량지좌신용우인공유산수술중적마취작용。방법회고성분석135례인공유산환자적림상자료，근거수술마취사용지좌신적불동제량분위저제량조、중제량조화고제량조，각45례，분별급여이병분화0.05，0.075，0.10 mg/kg적지좌신진행마취，비교3조환자적마취효과、궁축동통시각모의평분( VAS평분)이급불량반응발생정황。결과3조환자적총유효솔균위100.00%，중제량조화고제량조환자적현효솔균현저고우저제량조（ P＜0.05）；술후15，30 min중제량조화고제량조환자적궁축동통VAS평분현저저우저제량조（ P＜0.05）；총불량반응발생솔고제량조환자현저고우저제량조（ P＜0.05），이중제량조여저제량조무현저성차이（ P＞0.05）。결론이병분연합0.075 mg/kg지좌신용우인공유산，마취효과호，차불량반응발생솔저。
Objective To investigate the anesthetic effects of propofol combined with different doses of dezocine in artificial abortion. Methods The clinical data in 135 cases of artificial abortion in our hospital were performed the retrospective analysis. According to the different doses of dezocine in anesthesia, the patients were divided into the low-dose group, middle-dose group and high-dose group, 45 cases in each group. The three groups were given propofol and dezocine 0. 05, 0. 075, 0. 10 mg/kg for conducting anesthesi-a. The anesthetic effects, uterine contraction pain VAS scores and occurrence situation of adverse reactions were compared among the three groups. Results The total effective rate of the three groups was 100. 00%; the significantly effective rates of the middle-dose group and high-dose group were significantly higher than that of the low-dose group ( P < 0. 05 ) . The uterine contraction pain VAS score at postoperative 15, 30 min in the middle-dose group and high-dose group were significantly lower than that in the low-dose group ( P < 0. 05 ); the overall incidence rate of adverse reactions in the high-dose group was significantly higher than that in the low-dose group ( P < 0. 05 ) , while the difference in the overall incidence of adverse reactions had no statistically significant difference between the middle-dose group and the low-dose group ( P > 0. 05 ) . Conclusion :Propofol combined with dezocine 0. 075mg/kg for artificial abortion has the good anesthetic effects and low incidence of adverse reactions.
