中国药业
中國藥業
중국약업
CHINA PHARMACEUTICALS
2015年
9期
82-83
,共2页
CT增强扫描%碘佛醇%不良反应%应对方法
CT增彊掃描%碘彿醇%不良反應%應對方法
CT증강소묘%전불순%불량반응%응대방법
CT enhanced scan%ioversol%adverse reaction%coping methods
目的:观察并探讨CT增强扫描中碘佛醇的不良反应及应对方法。方法选择2012年6月至2014年5月行CT增强扫描并应用碘佛醇为对比剂的患者1256例,统计所有CT增强扫描成功患者注射碘佛醇前及注射后48 h内血清学、肾功能、心电图以及其他不良反应情况。结果注射后48 h内有14例患者血肌酐值及尿素氮值均显著升高,与注射前血肌酐值、尿素氮值比较有显著性差异( P<0.05)。注射碘佛醇后Ⅱ导联、T波以及avF等心电图异常发生率为2.07%,一过性心率异常发生率为2.55%,一过性血压升高发生率为3.26%,一过性轻微热感发生率为3.82%,一过性面部潮红发生率为3.98%,头晕、恶心发生率为1.75%,注射部位即时肿胀发生率为2.71%,无中度、重度不良反应发生。结论 CT增强扫描中碘佛醇尽管不良反应发生率相对较低,但仍需引起重视,必须采取恰当的应对方法。
目的:觀察併探討CT增彊掃描中碘彿醇的不良反應及應對方法。方法選擇2012年6月至2014年5月行CT增彊掃描併應用碘彿醇為對比劑的患者1256例,統計所有CT增彊掃描成功患者註射碘彿醇前及註射後48 h內血清學、腎功能、心電圖以及其他不良反應情況。結果註射後48 h內有14例患者血肌酐值及尿素氮值均顯著升高,與註射前血肌酐值、尿素氮值比較有顯著性差異( P<0.05)。註射碘彿醇後Ⅱ導聯、T波以及avF等心電圖異常髮生率為2.07%,一過性心率異常髮生率為2.55%,一過性血壓升高髮生率為3.26%,一過性輕微熱感髮生率為3.82%,一過性麵部潮紅髮生率為3.98%,頭暈、噁心髮生率為1.75%,註射部位即時腫脹髮生率為2.71%,無中度、重度不良反應髮生。結論 CT增彊掃描中碘彿醇儘管不良反應髮生率相對較低,但仍需引起重視,必鬚採取恰噹的應對方法。
목적:관찰병탐토CT증강소묘중전불순적불량반응급응대방법。방법선택2012년6월지2014년5월행CT증강소묘병응용전불순위대비제적환자1256례,통계소유CT증강소묘성공환자주사전불순전급주사후48 h내혈청학、신공능、심전도이급기타불량반응정황。결과주사후48 h내유14례환자혈기항치급뇨소담치균현저승고,여주사전혈기항치、뇨소담치비교유현저성차이( P<0.05)。주사전불순후Ⅱ도련、T파이급avF등심전도이상발생솔위2.07%,일과성심솔이상발생솔위2.55%,일과성혈압승고발생솔위3.26%,일과성경미열감발생솔위3.82%,일과성면부조홍발생솔위3.98%,두훈、악심발생솔위1.75%,주사부위즉시종창발생솔위2.71%,무중도、중도불량반응발생。결론 CT증강소묘중전불순진관불량반응발생솔상대교저,단잉수인기중시,필수채취흡당적응대방법。
Objective To observe the adverse reactions and coping methods of ioversol in CT enhanced scan. Methods 1 256 patients with enhanced CT scan and ioversol as contrast agent in our hospital from June 2012 to May 2014 were selected and the adverse re-actions situation of the serology, renal function, EKG, etc. before and within 0-48 h after injecting ioversol were performed the statis-tics. Results The serum creatinine and blood urea nitrogen values in 14 cases were significantly increased, which showed the statistical-ly significant differences compared with those before injecting ioversol ( P < 0. 05 ) . The occurrence rate of EKG abnormality in lead II, T wave and avF after injection of ioversol was 2. 07%, the occurrence rate of transient abnormal heart rate was 2. 55%, which of blood pressure was 3. 26%, which of slight fever sensation was 3. 82% and which of transient facial flushing was 3. 98%, the occurrence rate of dizziness and nausea was 1. 75%, the occurrence rate of instant swelling at the injection site was 2. 71%;no moderate and severe adverse reactions occurred. Conclusion Although the adverse reaction of ioversol in CT enhanced scan has relatively lower occurrence rate, but which needs to pay attention to and the appropriate coping methods should be adopted.